Résumé
Voltammetric analysis at platinum and gold rotating disc electrode [RDE] in 0.1 mol 1[-1] sulphuric acid has been applied for the determination of the active ingredient in solid dosage form. Non zero intercept in the limiting current versus concentration plot was proportionally good to excellent for the solid dosage form and is free from interference from adsorption on the electrodes. All of the dosage forms proved amenable to rapid voltammetric determination with a means standard deviation of 1.2
Sujets)
Platine , Or , Technologie pharmaceutique/instrumentation , Acides sulfuriques/composition chimique , Préparations pharmaceutiques/analyse , Conception d'appareillage , Formes posologiques , Techniques électrochimiquesRésumé
The violet color complex FeSal[+] was prepared by reaction of Salicylic acid and Ferric Chloride in acidic medium up to pH 3.5 in formate buffer at ionic strength 0.1 M. Reduction kinetics of FeSal[+] complex at pseudo first order condition have been studied spectrophotometrically by a reductant i.e. Hydroquinone. Reduction behaviour shows that reduction is much fast and pH dependent. A mechanism to account for observation is also proposed along with the rate law