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@#Propriospinal myoclonus （PSM） is a rare movement disorder. Three types of PSM have been reported：symptomatic，idiopathic and functional PSM. PSM at sleep onset is a subtype of idiopathic PSM. The current study summarized the clinical and neurophysiological characteristics of different types PSM. Methods The current study included 2 cases of PSM at sleep onset，2 cases of functional PSM，1 case of symptomatic PSM. Results Two patients with PSM at sleep onset had chronic course. Abdominal jerk was the main complaint，occurring at sleepwake transition. Mental disorders were happened in two cases with functional PSM，one of whom had various patterns of jerk and propagation. Neurophysiological examination showed that functional PSM had longer duration of muscle burst and faster velocity of recruitment. Moreover，myoclonic status was observed in PSM at sleep onset and symptomatic PSM. Conclusion PSM showed specific clinical neurophysiological characteristics according to different types. Differential diagnosis is required in clinics.
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@#Objective To investigate the clinical features and prognosis of anterior circulation cerebral infarction secondary to cervical artery dissection.Methods Sixty one patients with cervical artery dissection (CAD) secondary to anterior circulation cerebral infarction treated in Department of Neurology of North Jiangsu People’s Hospital from January 2016 to December 2020 were included consecutively.And 67 patients with large artery atherosclerosis (LAA) cerebral infarction complicated with moderate to severe carotid artery stenosis who were hospitalized at the same time were enrolled for comparison.The clinical data and prognosis between the two groups were compared.Results Unifactorial analysis showed that the average age of CAD cerebral infarction group was younger,the incidence of head and neck pain and monocular amaurosis was higher,the proportion of massage trauma fatigue history was higher,the incidence of hypertension and smoking history was higher in LAA cerebral infarction group.The comparison of the two hematologic examinations showed that the erythrocyte count was higher in the CAD cerebral infarction group,and the D-dimer,cholesterol,glycated hemoglobin,and uric acid values were higher in the LAA cerebral infarction group.Binary logistic regression analysis showed that the history of massage trauma fatigue was more correlated with CAD cerebral infarction,while older age and smoking history were more correlated with LAA cerebral infarction.The improvement of NIHSS scores during hospitalization in the CAD cerebral infarction group was more significant than that in the LAA cerebral infarction group,and the difference was statistically significant.There were no significant differences in 90 day prognosis,mortality,and reinfarction rate within 6 months between the two groups.Conclusion The correlation between the history of massage trauma and fatigue and CAD cerebral infarction was greater,and the correlation between the older age and smoking history and LAA cerebral infarction was greater.The improvement of NIHSS score in CAD cerebral infarction group during hospitalization was more obvious than that in LAA cerebral infarction group,which was statistically significant.There were no significant differences in 90 days prognosis,mortality and 6 month reinfarct rate between the two groups.
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OBJECTIVE:To establish the quality standard of Compound niubangzi buccal tablets.METHODS:Lonicerae japonica and Paeonia suffruticosa in the formulation were identified by TLC,and the content of arctiin in the tablets was determined by HPLC.RESULTS:The TLC spots were clear,well-isolated and distinctive.The linear range of arctiin was 0.586～5.274 ?g(r=0.999 9)and its average recovery was 98.94%(RSD=1.68%,n=9).CONCLUSION:The established quality standard can be used for the quality control of Compound niubangzi buccal tablets.