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Journal of Korean Medical Science ; : 398-402, 2009.
Article Dans Anglais | WPRIM | ID: wpr-79580

Résumé

This study evaluated the value of procalcitonin (PCT) levels in pleural effusion to differentiate the etiology of parapneumonic effusion (PPE). Forty-one consecutive PPE patients were enrolled and were divided into bacterial and non-bacterial PPE. Blood and pleural effusion samples were collected for PCT measurement on admission and analyzed for diagnostic evaluation. PCT of pleural fluid was significantly increased in the bacterial PPE group (0.24 ng/mL) compared to the non-bacterial PPE group (0.09 ng/mL), but there was no significant difference for serum PCT. A PCT concentration of pleural fluid >0.174 ng/mL (best cut-off value) was considered positive for a diagnosis of bacterial PPE (sensitivity, 80%; specificity, 76%; AUC, 0.84). Pleural effusion PCT in the bacterial PPE is significantly different from those of the non-bacterial PPE and control groups, so the diagnostic use of PCT still warrants further investigation.


Sujets)
Sujet âgé , Femelle , Humains , Mâle , Adulte d'âge moyen , Infections bactériennes/diagnostic , Calcitonine/analyse , Diagnostic différentiel , Épanchement pleural/diagnostic , Pneumopathie infectieuse/diagnostic , Valeur prédictive des tests , Précurseurs de protéines/analyse , Courbe ROC
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