A Case of Eosinophilic Gastroenteritis of Small Bowel with a Rupture

Eosinophilic gastroenteritis is a rare disease of unknown etiology. It is characterized by the infiltration of the gastrointestinal tract by mature eosinophils, and increased peripheral eosinophil count and associated with various food allergies. Clinical manifestations were related to the site of histologic infiltration in the wall and the segment of the involved gastrointestinal tract. Recently, the authors experienced one case of eosinophilic gastroenteritis of the small bowel with spontaneous rupture that was managed by segmental resection of ileum and end to end anastomosis. Four years previous, he has undergone segmental resection of the ileum due to ileum perforation of unknown etiology. The peripheral blood eosinophil count of this case was normal but the IgE level was elevated. Microscopically, there was a dense infiltration of eosinophils throughout the entire thickness of the ileal wall, particularly in the muscle layer. The patient recovered well, but had one episode of abdominal pain with diarrhea and those symptoms were improved following the administration of corticosteroids. A brief review of the etiology, pathology, clinical features, diagnosis and management of this disease is presented.

Eosinophilic Granuloma of the Lung

Eosinophilic granuloma of the lung, first described by Farrinaci et al. in 1951, is rare. A 35-year-old male smoker presented with recurrent pneumothorax. Open thoracotomy with bleb resection and biopsy was performed. Microscopically there was histological changes consistent with typical eosinophilic granuloma and intertitial fibrosis. The Langerhans cells showed positive reaction for S-100 protein and typical Birbeck granules in their cytoplasm. A brief summary of histopathological aspect of this disease and a review of literature are presented.

Pulmonary Lymphangioleiomyomatosis: A case report

Lymphangioleiomyomatosis(LAM) is a rare disease of women of child-bearing age in which there is progressive hyperplasia of atypical smooth mucle along lymphatics in the lung, and/or axial lymphatics in the thorax and abdomen, resulting in honeycombing of lung. Interestingly there has been a speculation that it represents a forme furste or incomplete expression of tuberous sclerosis complex. This is based on the observation that patients with tuberous sclerosis can manifest pulmonary lesions indistinguishable from LAM. We report a case of LAM occuring in a 39-year-old female, who complained of recurrent pneumothorax, chest pain and shortness of breath. Three years ago, the patient had right nephrectomy under the diagnosis of ruptured angiomyolipoma. A X-ray film of the chest showed honeycombing with a diffusely reticulonodular pattern and cyst-like spaces. She had a characteristic facial appearance of adenoma sebaceum, which her father and uncle had. Microscopically, the lung showed a marked smooth muscle proliferation around the slit-like lymphatic spaces and also some respiratory bronchioles.

Diagnostic Features of Fine Needle Aspiration Cytology of Pleomorphic Adenoma, Adenoid Cystic Carcinoma, and Mucoepidermoid Carcinoma of Salivary Gland / 대한세포병리학회지

The evaluate the diagnostic findings of salivary gland tumors, we reexamined aspiration cytology smears of 7 cases of pleomorphic adenoma, 3 cases of adenoid cystic carcinoma, and 3 cases of mucoepidermoid carcinoma, performed during April 1986 to March 1990, which were comfurmed by surgical excision and histologic diagnosis. The results obtained are summarized as follows : 1. All cases of pleomorphic adenoma showed branching cellular clusters of epithelial and myoepithelial cells. Acellular elements including myxomatous and chondroid components were observed. There were no cellular pleomorphism and nucleoli. Keratinizing squamous epithelial cells and keratin pearls were noted. 2. The smears of adenoid cystic carcinoma showed cell balls or cell cords containing a central hyaline core. Nuclear atypism and the nucleoli were frequently observed. There were no keratinizing squamous epithelial cells. 3. The smears of mucoepidermoid carcinoma showed mainly sheets or clusters of intermediate cells and some mucin-producing cells. Some nuclear pleomorphism was observed. Mucinous material and many inflammatory cells were present in the background.