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Zhonghua nankexue ; Zhonghua nankexue;(12): 539-541, 2013.
Article de Chinois | WPRIM | ID: wpr-350864

RÉSUMÉ

<p><b>OBJECTIVE</b>To evaluate the efficacy of daily low-dose tadalafil in the treatment of erectile dysfunction (ED) following pelvic fracture-induced urethral injury (PFUI).</p><p><b>METHODS</b>Based on the length of time between pelvic fracture and the patients' clinic visit, we divided 42 PFUI-caused ED patients into groups A (< 1 month), B (6-24 months) and C (> 24 months). We treated them with tadalafil at 5 mg daily for 12 weeks consecutively, followed by evaluation of the therapeutic effect using IIEF-5 questionnaire and Sexual Encounter Profile (SEP) diaries.</p><p><b>RESULTS</b>Thirty-four patients (83.3%) completed the investigation and all responded well to tadalafil medication. Group A showed significant differences from B and C in the increase of IIEF-5 scores and the positive rate of SEP.</p><p><b>CONCLUSION</b>Daily low-dose tadalafil helps penile rehabilitation in ED patients following PFUI, and the earlier the medication is initiated, the better the effect will be.</p>


Sujet(s)
Adulte , Humains , Mâle , Carbolines , Utilisations thérapeutiques , Relation dose-effet des médicaments , Dysfonctionnement érectile , Traitement médicamenteux , Fractures osseuses , Pelvis , Plaies et blessures , Tadalafil , Résultat thérapeutique , Urètre , Plaies et blessures
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