Résumé
Objective@#To evaluate the effects of total extraperitonal herniorrhaphy on pain and effusion in patients with surgical area.@*Methods@#The clinical data of 58 cases of inguinal hernia admitted to the First Hospital of Shanxi Medical University from January 2017 to January 2018 were retrospectively analyzed.Complete extraperitoneal inguinal oblique hernia repair was performed under laparoscopy under general anesthesia.The patients were divided into two groups by the single or double of admission date number.The observation group(A group, 32 cases) received post-operative intraoperative pressure homemade ice bags, the control group(B group, 26 patients) was placed in normal temperature saline bag after operation.The degree of pain in patients was evaluated by numerical scoring method.The time of exit, discharge, accumulation rate and recurrence rate of hernia were analyzed.@*Results@#The differences in pain score, pain score during floor movement, and regional efflux rate between A group and B group were statistically significant[(2.11±0.97)points vs.(2.45±1.21)points, (2.63±1.89)points vs.(2.76±1.95)points, 0 case vs.2 cases, t=2.745, 4.189; χ2=1.15, all P<0.05]. The time of discharge from hospital and discharge after surgery in A group and B group were (19.16±9.22)h vs.(19.76±10.52)h, (34.85±7.43)h vs.(37.56±8.91)h, the difference was not statistically significant(t=1.790, 0.834, all P>0.05).@*Conclusion@#After laparoscopic repair of total extraperitonal herniorrhaphy, the area ice pack can achieve the purpose of relieving pain in the surgical area and reducing the accumulation of fluid in the surgical area.
Résumé
Objective To evaluate the effects of total extraperitonal herniorrhaphy on pain and effusion in patients with surgical area.Methods The clinical data of 58 cases of inguinal hernia admitted to the First Hospital of Shanxi Medical University from January 2017 to January 2018 were retrospectively analyzed.Complete extraperitoneal inguinal oblique hernia repair was performed under laparoscopy under general anesthesia .The patients were divided into two groups by the single or double of admission date number.The observation group(A group,32 cases) received post－operative intraoperative pressure homemade ice bags ,the control group ( B group,26 patients) was placed in normal temperature saline bag after operation.The degree of pain in patients was evaluated by numerical scoring method. The time of exit,discharge,accumulation rate and recurrence rate of hernia were analyzed.Results The differences in pain score,pain score during floor movement ,and regional efflux rate between A group and B group were statistically significant[(2.11 ±0.97)points vs.(2.45 ±1.21) points,(2.63 ±1.89) points vs.(2.76 ±1.95) points,0 case vs.2 cases,t ＝2.745,4.189;χ2 ＝1.15,all P＜0.05].The time of discharge from hospital and discharge after surgery in A group and B group were (19.16 ±9.22) h vs.(19.76 ±10.52) h,(34.85 ±7.43) h vs.(37.56 ± 8.91) h, the difference was not statistically significant ( t ＝1.790, 0.834, all P ＞0.05 ).Conclusion After laparoscopic repair of total extraperitonal herniorrhaphy ,the area ice pack can achieve the purpose of relieving pain in the surgical area and reducing the accumulation of fluid in the surgical area .
Résumé
Objective To study the effects of puerarin on proliferation and apoptosis of human gastric cancer MGC-803 and AGS cells.Methods Human gastric cancer cells were treated with puerarin at different concentrations.MTT assay was used to test cell proliferation and FCM was used to detect cell apoptosis.Results The inhibition rates had upwarded trend with increasing concentrations (MGC-803:1.24 ％,2.80 ％,15.10 ％,18.55 ％,59.65 ％; AGS:15.59 ％,25.31％,30.25 ％,36.91％,64.47 ％),when treated with puerarin at different concentrations (1.5,3.0,6.0 12.0,24.0 mmol/L) for 48 hours.Apoptosis rates gradually increased with increasing concentrations (MGC-803:5.49 ％,9.53 ％,13.81％; AGS:6.23 ％,16.38 ％,25.99 ％),when treated with puerarin at different concentrations (0,12.0,24.0 mmol/L) for 24 hours.Conclusion Puerarin inhibits proliferation and induces apoptosis of human gastric cancer cells MGC-803 and AGS.