Effects of paternal age on pregnancy outcomes in frozen-thaw embryo transfer cycles / 现代泌尿外科杂志

【Objective】 To observe the effects of paternal age on the pregnancy outcomes in frozen embryo transfer (FET) cycles. 【Methods】 The clinical data of two groups after propensity score matching (PSM) were retrospectively analyzed, including 738 cycles in the 0.05). The clinical pregnancy rate (52.2%vs. 67.2%) and live birth rate (41.1% vs. 57.2%) decreased in the 40-60 year group compared with those in the 0.05). 【Conclusion】 Advanced paternal age decreases clinical pregnancy rate and live birth rate.

Clinical application of Bakri balloon in postpartum hemorrhage of placenta prepartum / 中国现代医生

Objective To analyze the effect of Bakri balloon and intrauterine gauze packing combined with bilateral ligation of uterine artery ascending branch (abbreviation: intrauterine packing artery ligation) in postpartum hemorrhage of placenta previa. Methods We selected 63 cases of placenta previa hemorrhage during caesarean section from January 2013 to December 2017 in our hospital. Participants were divided into Bakri balloon group with 33 cases and intrauterine packing artery ligation group with 30 cases according to different treatment methods. In the Bakri balloon group, Bakri balloon was used to stop bleeding and intrauterine packing artery ligation group was treated with intrauterine gauze packing combined with bilateral ligation of uterine artery ascending branch to stop bleeding. Intraoperative blood loss, operation time, blood loss 24 hours after operation, number of blood transfusions and the rate of hysterectomy were analyzed. Results The blood loss and blood transfusion in the Bakri balloon group were significantly lower than those in the ligation group (P＜0. 05). The operation time was also significantly lower than that in the ligation group(P＜0. 05). There was no significant difference in blood loss 24 hours after operation between the two groups(P＞0. 05). All patients in the Bakri balloon group stopped bleeding successfully, while 2 cases in the ligation group received uterine artery embolization. No hysterectomy was performed in both groups. Conclusion Bakri balloon for the treatment of postpartum hemorrhage of placenta previa is simple, safe and effective. Mastering operation skills can shorten the operation time of balloon and reduce intraoperative blood loss. lt can be applied at any time for postoperative massive hemorrhage which is worthy of promotion in clinic.

The study between temporal bone HRCT and operations in congenital abnormality of external and middle ear / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#We explore the deformity degrees of external ear, mastoid process, tympanic cavity and auditory ossicle by the HRCT features of bilateral and unilateral patients of congenital abnormality of external and middle ear for preoperative analysis and selection for surgical approaches.@*METHOD@#Twenty-nine patients were enrolled in our study, and HRCT were performed on all patients. There were 23 unilateral ears deformity (13 right and 10 left), 6 patients with bilateral ears deformity in the study group. Nineteen patients (19 ears) were treated with operations.@*RESULT@#The deformity degree of auricle was correlated with that of external auditory meatus, and mastoid process develops bad aeration extent with bad tympanic cavity development in 35 ears in our research. We got data of shortest distance from tympanic cape to atresia board in HRCT, (0.59 +/- 0.13)cm in comparison group, (0.45 +/- 0.19)cm in unilateral deformity group, (0.32 +/- 0.12)cm in bilateral deformity group, and there were significant differences compared the two deformity groups with the comparison group. There were 1 ear with normal auditory ossicle (2.86%), 5 ears with fixation of stapes foot board (14.29%), 3 ears with no auditory ossicle (8.57%); 26 ears with malleus and incus abnormality (74.29%). Abnormality of malleus was always concomitant with that of incus. Degeneration of malleus, the joint amalgamation of malleus and incus were discovered mostly in this research.@*CONCLUSION@#The deformity degree of auricle is correlated with that of external auditory meatus, and mastoid process develops bad aeration extent with bad tympanic cavity development in 35 ears in our research. The shortest distance from tympanic cape to atresia board in HRCT in unilateral ears deformity group are shorten 0.15 cm in that of comparison group. And that of bilateral ears deformity group are shorten 0.25 cm in that of comparison group. The main abnormality of auditory ossicle in our research present in both malleus and incus, and degeneration of malleus and the joint amalgamation of malleus and incus are main types.

Establishment of a C57BL/6N mouse model of giardiasis / 中华医学杂志(英文版)

<p><b>OBJECTIVE</b>To establish a C57BL/6N mouse model infected with Giardia lamblia (G. lamblia) isolates from human origin.</p><p><b>METHOD</b>Two groups of C57BL/6N mouse were inoculated with purified cysts of two G. lamblia isolates (CD and XZ) by gavage separately. Patterns and curves of cyst excretion of the infected mice were observed and summarized. Histopathological changes of the small intestines of the infected mice were observed.</p><p><b>RESULTS</b>Thirty-six mice receiving 1 x 10(4) cysts each were all infected. The C57BL/6N mouse showed high susceptibility to G. lamblia infection. There was no notable distinction between the two groups of the mice infected by the cysts of CD and XZ isolates. Cyst excretion occurred with intermittence. Of 36 infected mice, 32 (89%) passed cysts intermittently and 4 (11%) others persistently. The latent period of cyst excretion was 0 - 3 days p.i. (post-inoculation). The interruption of cyst excretion ranged from 12 to 20 days p.i. The fastigium of the cyst excretion was on day 6 p.i. The peak count of the cysts passed during a 2 h collection period was 2.3 x 10(7)/g fecal specimen. Edema, inflammation, cell infiltration, small blood vessels congestion, mitotic figures and mucosa necrosis appeared in sections of intestines.</p><p><b>CONCLUSION</b>C57Bl/6N mouse is a suitable animal model of G. lamblia.</p>