RÉSUMÉ
Objective:To observe the clinical effects of targeted percutanous ozone ablation on lumbar disc herniation (LDH) patients with high intensity zone (HIZ) in lumbar disc annulus fibrosus on MRI T2 weighted imaging.Methods:136 LDH patients with HIZ in lumbar disc annulus fibrosus on MRI T2 were divided into two groups according to therapy methods.In group A,75 patients were injected with 2 ~5 mL of 40 μg/mL mixture of O3 and O2 after targeted percutanous puncturing under the guidance of X-Ray machine with C-type arm.In group B,61 patients were treated with conservative treatment.MacNab score criterion and Oswestry disability index (ODI) were used in assessment of the efficacy.Results:Except 24 patients,all the other cases were followed up for 18 ~ 44 months.At the postoperative 1st,2nd,3rd,6th,9th,12th and 18th month,according to MacNab score criterion,the effective rates were respectively 88.00 %,90.67 %,93.33 %,89.39 %,84.85 %,78.13 % and 73.44 % in group A and respectively 68.85 %,62.30 % 55.74 %,61.82 %,58.12 %,54.17 % and 47.92 % in group B.There were significant differences between two groups at the same time point (P<0.05).At the postoperative 12th and 18th month,ODI was lower in group A,and there was no significant difference between two time points (P>0.05).But it was significant different with that preoperatively and in group B at the same time point (P<0.05).Conclusion:Targeted percutanous ozone ablation is an effective method with stable clinical efficacy in treating LDH with HIZ in lumbar disc annulus fibrosus on MRI T2 weighted imaging.