Résumé
OBJECTIVE:To evaluate the therapeutic effect of compound glycyrrhizin on atopic dermatitis(AD)in chil?dren.METHODS:60cases of AD were randomly divided into trial group and control group.Trial group(36cases)orally received compound glycyrrhizin tablets and control group(24cases)cyproheptadine tablets.Eloson cream was topically applied to both groups.The treatment course was8weeks with an interval of1week for both groups.RESULTS:The curative rate and total effective rate were52.8%and94.4%for trial group and12.5%and62.5%for control group respectively.The differences were significant between2groups(P
Résumé
Objective To study the protective effects of estrogen on brain injured by cerebral ischemia-reperfusion in ovariectomized rats.Methods 30 d after bilateral ovariectomy,the benzestrofol 100 ?g/(kg?d)were intramusculari injected in to the models of ovariectomied rats for 14 d. Then the rat models of focal cerebral ischemia-reperfusion were made. The expressions of CD54 and TNF-? in brain tissue were detected by immunohistochemistry. The apoptotic cells were assayed by TUNEL,and the ultramicrostructural changes of neuron membrane was observed by electron microscope. Results Compared with the ischemia-reperfusion group and ovariectomized group,the expressions of CD54 and TNF-? of brain tissue in the estrogen group were significantly lower,and the apoptosis was reduced (all P