Résumé
OBJECTIVE: To establish the method of the preparation and test for methyl salicylate glycoside (MSG) tablets. METHODS: MSG tablets were prepared with MSG as main drug and microcrystalline cellulose and sodium carboxymethyl starch as exipients. Its detection method was studied. RESULTS: After experimental study, the high performance liquid chromatography method for related substances detection and content determination of MSG tablets were established. CONCLUSION: The prescription is reasonable and the preparation technology is reliable. The HPLC method has high accuracy and sensitivity and can be used for MSG tablets test.
Résumé
The paper is to report the establishment of three methods for determination of methyl salicylate-2-O-beta-D-galactopyranoside (1-4)-beta-D-glucopyranoside (MSG) by HPLC, UV or potentiometric titration. The results determined by the three methods turned out to be of no significant difference (P>0.05). The method was chosen according to MSG difference test demands.
Sujets)
Anti-inflammatoires , Chimie , Chromatographie en phase liquide à haute performance , Méthodes , Hétérosides , Chimie , Structure moléculaire , Potentiométrie , Méthodes , Reproductibilité des résultats , Salicylates , Chimie , Sensibilité et spécificité , Spectrophotométrie UV , MéthodesRésumé
<p><b>OBJECTIVE</b>To select a proper Ganoderma luciderm strain for the fruiting body production.</p><p><b>METHOD</b>The strains were cultivated on the agar media and in the liquid media, respectively. Then the strains were inoculated onto the solid medium made from agricultural products (such as wheat bran, corn powder, wood meal, etc.) and cultured for a certain period.</p><p><b>RESULT</b>Strains, which were easier to produce polyporic tissues at the vegetative growth stage, would be more quickly to form fruiting body with high quality and yield of the spores.</p><p><b>CONCLUSION</b>Appearance of the polyporic tissues at the mycelium vegetative growth stage could be used as a marker for the strain selection for the G. luciderm substituted cultivation.</p>