Résumé
Objective: To evaluate the effect of Jinqijiangtang Tablet prepared by new technology on blood glucose and lipids in rats with type 2 diabetes. Methods: Type 2 diabetic rat model was established by high fat diet combined with STZ injection. Metformin was used for a positive drug in the present study. Fasting blood glucose, glycosylated serum protein, serum insulin, and insulin resistance index were determined to evaluate the hypoglycemic effect of Jinqijiangtang Tablet prepared by new technology. And serum triglyceride, cholesterol, high density and low density lipoprotein were observed to evaluate the lipid-lowering effect of Jinqijiangtang Tablet prepared by new technology. Results: Jinqijiangtang Tablet prepared by new technology and metformin both could reduce the fasting blood glucose and glycosylated serum protein, and improve glucose tolerance and insulin resistance. Jinqijiangtang Tablet could reduce the levels of cholesterol and HDL.Conclusion: Jinqijiangtang Tablet prepared by new technology can effectively improve insulin resistance, and it has a lipid-lowering effect.