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Prescription patterns play a critical role in healthcare delivery, affecting the efficacy of medication therapy and resource utilization. Rational prescribing practices are essential for safe and effective healthcare, necessitating comprehensive prescriptions containing medication details, prescriber information, and patient instructions. This review explores prescription completeness and rationality, utilizing WHO prescribing indicators and other completeness metrics, across Indian healthcare facilities. A systematic search was conducted in PubMed and Google Scholar for original research articles published between 2013 and 2023, focusing on WHO-recommended prescribing indicators and completeness criteria. Inclusion criteria covered articles in English, spanning primary, secondary, or tertiary care settings. Data from selected articles were extracted and analysed. Data were synthesized from sixty-seven studies, depicting various prescribing practices. The assessment encompassed prescribing, patient care, and facility indicators. Findings highlighted challenges such as illegible prescriptions, incomplete details, polypharmacy, brand name dominance, and inappropriate antibiotic use. Despite WHO recommendations, generic prescribing was limited. This review reiterates the need for interventions to enhance prescription quality, patient safety, and cost-effectiveness. Recommendations include adopting electronic prescribing systems, standardizing prescription formats, conducting regular prescription audits, implementing educational programs, promoting generic drug use, and adhering to essential medicines lists. These multifaceted strategies can improve prescribing practices and ultimately contribute to enhanced healthcare outcomes in India.
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The present investigation entitled “Efficacy of foliar feeding of Ca, Zn and Cu with and without Borax on Fruit drop and Bio-Chemical attributes of winter season guava (Psidium guajava L.) cv. L-49” was conducted at guava orchard of Kalyanpur nursery, Department of Fruit Science, Chandra Shekhar Azad University of Agriculture and Technology, Kanpur 208002 during 2019-2020. 39 guava trees with even size and vigour were selected and were sprayed with various concentrations of different nutrients (Ca(NO3)2 @ 0.50% and 1%), (ZnSO4 @ 0.50% and 1.0%) and (CuSO4 @ 0.60% and 0.80%) with and without Borax (1%). Thirteen treatments were replicated three times as part of the RBD (Randomised Block Design) investigation. Fruits were examined in the laboratory of the Department of Fruit Science, C.S.A.U.A&T., Kanpur, for their physical and biochemical characteristics. The results of the present study revealed that fruit drop (33.94%) and bio-chemical attributes that is, Total soluble solids (13.54 0Brix), Acidity (0.46 %) and Ascorbic acid (194.30 mg/100g pulp) were improved significantly with the use of ZnSO4 1.0% + Borax 1.0% (T10).
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The study focused to investigate the ‘Response of combined application of nutrient levels with microbial strains on crop growth, nodulation and yield of soybean (Glycine max (L.) Merrill.)’ at All India Coordinated Research Project (AICRP) on Integrated Farming System Research at College of Agriculture, Indore, Madhya Pradesh, India during kharif, 2019-20. The research was conducted in randomized block design (RBD) with 8 treatments, viz. Control with 75% RDF (T1), Control with 100% RDF (T2), 75% RDF with Bacillus megaterium and Bacillus mucilaginosus strains as seed treatment (T3), 100% RDF with Bacillus megaterium and Bacillus mucilaginosus strains as seed treatment (T4), 75% RDF with Bacillus megaterium and Bacillus mucilaginosus strains as foliar application at 30 and 45 DAS (T5), 100% RDF with Bacillus megaterium and Bacillus mucilaginosus strains as foliar application at 30 and 45 DAS (T6), 75% RDF with Bacillus megaterium and Bacillus mucilaginosus strains as seed treatment + foliar application of Bacillus megaterium and Bacillus mucilaginosus strains at 30 and 45 DAS (T7) and 100% RDF with Bacillus megaterium and Bacillus mucilaginosus strains as seed treatment + foliar application of Bacillus megaterium and Bacillus mucilaginosus strains at 30 and 45 DAS (T8). The seed yield of soybean increased to the tune of 14.26 and 19.72 per cent with application of 100% RDF with Bacillus megaterium and Bacillus mucilaginosus strains as seed treatment + foliar application of Bacillus megaterium and Bacillus mucilaginosus strains at 30 and 45 DAS compared to control. Among all the treatments, crop growth and yield (1139 kg/ha) were observed highest with 100% RDF with Bacillus megaterium and Bacillus mucilaginosus strains as seed treatment + foliar application of Bacillus megaterium and Bacillus mucilaginosus strains at 30 and 45 DAS.
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Background: Dental caries is one of the most prevalent oral diseases of public health concern affecting elder people. The main reasons for caries arise in elderly people are increase in sugar consumption, poor oral hygiene, microbial plaque, periodontal disease, dietary habits, low socioeconomic status and infrequent dental visits. The oral hygiene is essential to general health and quality of life. Methods: A descriptive cross-sectional study was conducted among 246 elder people. Systematic random sampling was used for data collection. The data collection was done between 15 April to 07 May 2017. Results: The overall prevalence of dental caries in study population was 88.57%. The mean DMFT of all study participants was 17.13 (SD=10.48; participants were allocated a DMFT of 32). Majority of elder people (56.33%) had experience of pain and discomfort in their teeth within 12 months. The gender, marital status, diet, socio-economic status, medication, method of cleaning, frequency of cleaning, dental visit and tobacco chewing were factors that determines dental caries. Regular dental checkup (11%) was very poor. Majority of respondents preferred tea with sugar, biscuits/cake, chocolate and soft drinks (64%). Conclusions: The study showed that the prevalence of dental caries among elderly people in Rajdevi Rural Municipality, Rautahat District, Nepal was high. The awareness should be provided to local residents regarding the importance of good brushing habits and regular dental visits. Oral health policies are needed revised and implemented focusing on the special needs of this population to improve their quality of life.
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A field experiment was carried out at Soil Conservation and Water Management Farm of C S Azad University of Agriculture and Technology, Kanpur during Zaid seasons i.e. 2022 and 2023 to assess the effect of irrigation scheduling and integrated nutrient management on blackgram.The experiment consisted of three irrigation schedulesviz.I1:0.4 IW/CPE, I2:0.6 IW/CPE, I3:0.8 IW/CPE, along with five integrated nutrient management options viz.F1: 100% RDF, F2:125% RDF.F3: 75% RDF + 2.5 ton FYM/ha,F4: 50 % RDF + 5 ton FYM/ha.F5: 50% RDF + 2.5 ton FYM/ha + 1 tonvermi-compost. The experiment was conducted in Split Plot Design replicated thrice irrigation scheduling systems in main plots and integrated nutrient management in sub plots. The result clearly revealed that significantly higher growth attributes viz plant height (35.25 cm and 37.56 cm), number of branches plant-1 (8.87 and 9.21), number of plant leaves (19.96 and 20.29) at harvest and yield attributes viz number of pod per plant (27.80 and 30.10) no of seed per pod (6.62 and 6.91) and also higher seed yield (9.30 q ha-1 and 9.90 qha-1 ), stover yield(23.21 q ha-1 and 24.03 q ha-1) were recorded with I3: 0.8 IW/CPE compared to I1: 0.4 IW/CPE and I2: 0.6 IW/CPE. Among the integrated nutrient management significantly higher growth attributes viz plant height (36.12 cm and 38.07 cm), number of branches plant-1 (9.01 and 9.32), number of plant leaves (20.05 and 20.45) at harvest and yield attributes viz number of pod per plant (28.44 and 30.17) no of seed per pod (7.05 and 7.37) and also higher grain yield (9.73 q ha-1 and 10.27 qha-1 ), stover yield(23.55 q ha-1 and 24.76 q ha-1) were recorded with F5:50% RDF + 2.5 ton FYM/ha + 1 ton vermi-compost as compared to other integrated nutrient management protocol.
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A field experiment was conducted during 2018 and 2019 at the Agronomy Research farm of A.N.D. University of Agriculture and Technology, Kumarganj, Ayodhya, UP to evaluate the effect of foliar application of macro and micronutrients on yield and nutrient uptake of rice (Oryza sativa L.). The experiment consists of 10 treatment combinations with some foliar application macro and micronutrients two foliar spray tillering stages and a panicle initiation stage which were laid out in randomized block design with three replications. The results revealed maximum grain yield (38.50 and 40.40 q ha-1), straw (51.90 and 54.60 q ha-1), and harvest index (42.64 and 42.53 %) with treatment T10-75% RDF + WSCF @ 0.5 % (19:19:19) + ZnSO4 @ 0.5 % + Boron @ 0.25 % which was statistically at par with T3- 125 % RDF and significantly superior over rest of the treatments during both the years ., was recorded Similarly significant improvement in nutrient uptake (N, P, K, S, Zn, and B) by rice was observed in T10. Thus, it can be concluded that the application of 75% RDF + WSCF @ 0.5 % (19:19:19) + ZnSO4 @ 0.5 % + Boron @ 0.25 % can improve the yield and nutrient uptake.
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Bamboo is a versatile group of fastest growing plant which is capable of providing ecological, economical, environmental and livelihood security to the people. The study investigates uses, contribution, scope of the green gold plant bamboo. The review of this study showed that bamboo has evolved into a highly valuable and superior plant which serves for food, fodder and many more also bamboo-based products have the potential to replace wood, plastics in a variety of industrial uses without harming the nature by maintaining sustainability. So in this review paper comprehensive overview of the recent literatures about multidimensional scope of bamboo in form of its greatest potential is being discussed.
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To assess the significance of mulching and nutrients on the performances of Strawberry (Fragaria x ananassa) with respect to the qualitative character's during 2019–20, a field experiment was carried out at the Horticulture Research Farm-1 of the Department of Horticulture, School of Agricultural Sciences and Technology, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya-Vihar, Rae Bareli Road, Lucknow. The experiment was laid out in RBD having three replications. The result revealed significantly highest Tss (11.28)0Brix, Total Sugar (8.98%), Reducing Sugar (6.41%), Non Reducing Sugar (2.57%), Acidity (0.31%) and Ascorbic Acid (41.90 mg/100g) in treatment T14 (Black polythene + Vermicompost 50% + NPK 50%) followed by the treatment T13 (Black polythene + FYM 50% + NPK 50%). Treatment T1 (the control), on the other hand, performed poorly in terms of all qualitative character’s. In light of the results, it can be said that using Black polythene with Vermicompost 50% + NPK 50% in strawberry increases all qualitative attributing characters, while Black polythene with FYM 50% + NPK 50% produced the second-best results.
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This review paper comprehensively examines the multifaceted effects of climate change on fruit crops, delving into physiological, phenological, and pest-related responses. Climate change, characterized by shifts in temperature, precipitation patterns, and extreme events, presents profound challenges to fruit crop cultivation and production. By analyzing the interplay between climate variations and fruit crops' physiological processes, flowering patterns, and susceptibility to pests, this paper aims to provide a comprehensive understanding of the intricate mechanisms underlying these interactions. The study encompasses the influence of drought, rainfall, temperature fluctuations, and pest dynamics on various fruit crops, ranging from mangoes and apples to bananas, grapes, and more. The review underscores the urgency of developing adaptive strategies to mitigate the adverse impacts of climate change on fruit crop production and quality.
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This research focuses on the functional characterization of 19 rhizobia strains isolated from Southern Rajasthan's Udaipur and Dungarpur districts, with an emphasis on their multiple Plant Growth Promoting (PGP) activities. Through a series of tests encompassing Indole-3-Acetic Acid (IAA) production, siderophore production, phosphate solubilization, ammonia production, and hydrogen cyanide (HCN) production, this study elucidates the diverse PGP potential of these rhizobia strains. The results showcase variations in IAA production, highlighting their ability to enhance root development and overall plant growth, while also revealing strains capable of siderophore production, indicating potential iron uptake facilitation. Furthermore, some strains exhibit phosphate solubilization, ammonia production, and HCN production capabilities, signifying their potential to improve nutrient availability and protect plants from pathogens. These findings underscore the promise of harnessing the PGP activities of these rhizobia strains for sustainable agricultural practices in Southern Rajasthan and similar agroecological regions, with implications for enhanced crop yields and soil health.
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The field experiment was carried out at Horticulture Research Farm No.1, Babasaheb Bhimrao Ambedkar University, Lucknow during Rabi season 2021-22. In this, twenty genotypes including check cultivars were evaluated to estimate the genetic variability, heritability and genetic advance for different characters. The experiment was laid out in Randomized Block Design (RBD) with three replications. Characters viz., days to 50% flowering, plant height, number of primary branches per plant, polar diameter of fruit, equatorial diameter of fruit, total soluble solids, number of fruits per cluster, average fruit weight, number of fruits per plant, marketable fruit yield per plant, unmarketable fruit yield per plant and total fruit yield per plant were studied during the experiment. Analysis of variance showed significant differences among genotypes for all the characters under study during the investigation. The Phenotypic coefficient of variance (PCV) was higher than the genotypic coefficient of the variation (GCV) for the characters studied. The highest genotypic coefficient of variation (GCV) was observed for unmarketable fruit yield per plant. The moderate GCV was reported for total fruit yield per plant followed by plant height and average fruit weight, polar diameter of fruit, no. of primary branches per plant, marketable fruit yield per plant and equatorial diameter of fruit whereas it was least for TSS followed by days to 50% flowering and number of fruits per cluster. Therefore these characters exhibited high heritability coupled with genetic advance thus show some scope for improvement through selection.
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Among the Kharif legumes clusterbean (Cyamopsis tetragonoloba L. Taub) is important crop and popularly known as “Guar” in India. A field experiment was conducted during Kharif 2013 at Agronomy Farm, S.K.N. College of Agriculture, Jobner, Jaipur (Rajasthan) to evaluate the weed management in clusterbean under the application of different agrochemicals and phosphorus levels. The treatments comprising 6 weed control treatments (Weedy check, one hand weeding at 20 DAS, two hand weeding at 20 and 40 DAS, pendimethalin at 0.75 kg/ha, imazethapyr at 100 g/ha and fenoxoprop-p-ethyl at 70 g/ha and four levels of phosphorus (0, 20, 40 and 60 kg/ha) assigned to main and sub plots of spilt plot design, respectively and replicated thrice. Results showed that HW twice at 20 and 40 DAS and pre emergence application of imazethapyr at 100 g/ha resulted significant reduction in weed density and weed dry matter in comparison to most of the treatments. Results further indicated that application of 60 kg P2O5/ha in clusterbean recorded the highest density and dry weight of weeds at all the stages. Maximum weed control efficiency was recorded under two hand weeding at 20 & 40 DAS.
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Fiberoptic bronchoscopy (FOB) has simplified the direct examination of the lungs and is widely used for diagnosis and therapy. Fiberoptic bronchoscopes occupy a significant proportion of cross-section area of central airways, which can affect lung mechanics and gas exchanges that may lead to desaturation and cardiac arrhythmia. This makes bronchoscopy in critically ill patients with respiratory failure even more challenging. Use of noninvasive mechanical ventilation (NIV) may help to avoid use of invasive mechanical ventilation in selected patients with acute respiratory failure. It has been shown to be useful in hypoxemic patients to facilitate bronchoscopic examination for bronchoalveolar lavage, bronchial brushing, endobronchial biopsy (EBB), and transbronchial lung biopsy (TBLB). Noninvasive mechanical ventilation has also been used to facilitate other endoscopic procedures including transesophageal echocardiography (TEE) and upper gastrointestinal endoscopy for diagnostic and therapeutic interventions in hypoxemic patients. Endobronchial ultrasound (EBUS) bronchoscope, having a wider diameter than a conventional bronchoscope, may have a more pronounced effect on lung mechanics and gas exchanges, and its use in patients on NIV has not been reported. Contraindications of EBUS are mostly relative and similar to FOB. There are several studies suggesting the safety of NIV-supported FOB in hypoxemic patients. We describe our experience of the first two EBUS bronchoscopies and transbronchial needle aspiration (TBNA) was done in hypoxemic patients with NIV support.
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Background: COVID-19 is a global pandemic started from Wuhan China in December 2019 and involved whole world including India. India has reported 3.48 crores cases and 4.81 lakhs death till December 31, 2021. Madhya Pradesh is among the top ten case load states in India affected by COVID. Initially, there was involvement of urban area of large cities followed by small rural area of Madhya Pradesh. Aims and Objectives: The aim of the study was to describe the epidemiological determinants of the COVID-19 in Sironj block of Vidisha district of Madhya Pradesh. Materials and Methods: This was a community-based cross-sectional study which included all laboratory positive COVID-19 cases from first reported case from April 3, 2020 to August 3, 2020 (first wave). The information was collected through predesigned proforma with the help of health workers in health services. MS Excel software used for data analysis. Results: Out of 132 positive cases, the majority of cases were between 15 and 35 years of age group with 2/3 cases of male predominance. More than 58% patients were asymptomatic at the time of diagnosis. There were on average 57.39 cases/Lakh population found during the study period while sample positivity rate was 13.73%. Cases were scattered around 41 major areas of Sironj block. Peak cases were observed around past 2 weeks of July 2020 during first wave of COVID-19. Conclusion: The focus must be placed around the ward/village where the number of active cases of COVID-19 is concentrated. It must be reconsidered on time to time basis.
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Crops need large quantity of potassium for enhancing their yield as well as quality. Pulses are important crops grown in India but their productivity is low. Among production inputs, recommendations for N and P fertilizers are made in most states with no K application resulting in imbalanced nutrient supply and lower crop yields.To quantify optimum dose for green gram ( Vigna radiata L.), a series of field experiments were conducted at Regional Research Station, CCS HAU, Bawal, Haryana, to assess the response of green gram to fertilizer potassium on coarse textured (Typic Haplustepts) soils of southern Haryana. After completion of research trials, crop was tested on farmer’s field through demonstrations and on farm trials (OFTs) to evaluate the response and adoptability of green gram as per the fertilizer potassium doses concluded in research experiment. Five levels of fertilizer potassium (0, 10, 20, 30 and 40 kg K2O ha-1) were evaluated for the response of green gram in randomized block design replicated thrice. The results of research trials revealed that the yield, protein content and growth parameters of green gram increased significantly with the application of fertilizer potassium @20 kg K2O ha-1. Significantly higher yield of green gram was recorded (5.87, 16.29, 19.23 and 22.36 %) due to application of 10, 20, 30 and 40 kg K2O ha-1, respectively over control. The total K uptake by green gram increased significantly with the incremental doses of potassium application which helped to prevent the depletion of available soil K and build-up its content in the soil. The mean K use efficiency varied from 38.30 to 54.15 and maximum (54.15 %) was recorded with the application of 20 kg K2O ha-1. The benefit cost ratio was also increased with the application of potassium and reflected in terms of additional returns per rupee (Rs. 10.94, 15.63, 12.17 and 10.72) invested on application of K @ 10, 20, 30 and 40 kg K2O ha-1, respectively. The farmer’s field trial results with 0 and 20 kg K2O ha-1 revealed that application of 20 kg K2O ha-1 increased the yield of green gram by 10.87% over control.
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Present study was undertaken to study the neurotoxicity of oral acrylamide (ACR) and its amelioration using α-tocopherol, reduced glutathione (GSH) and hot aqueous extract (HAE) of Ocimum sanctum. Forty five male Wistar rats were divided into 12 groups. The study showed a significant reduction in the body weight of the rats fed with ACR in comparison to the other groups while body weight was restored in the rats fed with α-tocopherol and HAE. Neurotoxicity in rats fed with ACR was evident with the results of histopathology and oxidative stress (high MDA and decreased activities of GSH, SOD, GST and CAT in brain). Co-administration of α-tocopherol and HAE lowered these changes however, there was no marked improvement seen in neural damage but improvement was evident in behavioral as well as physiological changes at a marked point. Histopathology of brain in ACR alone fed group showed extensive neural degeneration and massive deposition of fibrin which was substantially decreased and ameliorated with the co-administration of α-tocopherol and HAE. These results support the oxidative stress results as well. Our results suggests that α-tocopherol and HAE can be useful for protecting brain tissue against ACR induced neurotoxicity through minimizing the free radical mediated oxidative stress
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Spermatozoa undergoes array of signaling and intracellular pathways and ultimately become competent enough to accomplish fertilization. Hormones, ion channels and signaling molecules in both male and female reproductive tract show bidirectional cross play. The recent discovery of endocannabinoids and their receptors in male and female reproductive system opened new vistas for their research in regulating sperm function. Interestingly, endocannabinoids regulate sperm motility, capacitation, hyperactivity and eventually acrosome reaction. However, their complex intracellular pathways are still to be understood in regulating spermatozoa function. The present review highlights the major breakthrough research in the area of endocannabinoids in male reproduction and in more specific in sperm cells, and their association with regulation of sperm fertilizing competence
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Background: Anterior Support Ankle Foot Orthosis (A-AFO) is a fairly recent approach. There is dearth of studies relating to comparison of metabolic efficiency of A-AFO and P-AFO. Objective was to study the efficacy of A-AFO compared to P-AFO in foot drop patients, using gait and metabolic analysis.Methods: It was a cross over study, included foot drop patients who could walk with/ without orthosis. Patients having spasticity more than grade 2 (Modified Ashworth Scale) were excluded. The metabolic parameters measured were volume of Oxygen consumed at Standard Temperature and Pressure in l/min (VO2), Dry in l/min, Rate of Oxygen consumption (MET), Volume of Carbon dioxide produced in litre/min (VCO2). Along with various gait parameters, questionnaire about patient’s preference after 4 weeks was also incorporated.Results: A-AFO was significantly better than P-AFO in terms of VO2 and VCO2 (p value = 0.02 and 0.009 respectively) as well as in terms of subjective preference.Conclusions: A-AFO is comparable to P-AFO in terms of energy efficiency, gait parameters and subjective preference, hence should also be prescribed.
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Aim: The objective of the present study was to assess the impact of conjunctive use of wool waste, farm yard manure and chemical fertilizer on soil properties of Aridisol of Bikaner, Rajasthan, India. Methodology: After harvest of cabbage crop, soil samples were collected from the respective experimental plot of crop field by adopting the standard procedure. Bulk density, particle density, pH, electrical conductivity, organic carbon, available N, P, K, S, Zn, Cu, Mn, Fe, microbial count and dehydrogenase activity were estimated following the standard protocol. Results: Application of wool waste @ 7.5 t ha-1 along with FYM @ 7.5 t ha-1 (W1) significantly increased organic carbon and plant available nutrients (N, P, K, S, Zn, Cu, Mn, Fe) over control and rest of the treatment. but W1 and W2 (Wool waste @ 5 t ha-1 along with FYM @ 10 t ha-1) treatment was found at par with respect to nitrogen. Treatment W1 also gave significant performance of microbial count and dehydrogenase activity during experimental season over rest of the treatment. Application of each increasing level of recommended dose of fertilizer significantly enhanced all chemical and biological properties of soil. Application of wool waste @7.5 t ha-1 along with FYM @7.5 t ha-1 increased available macronutrients and micronutrients over control. Interpretation: It can be concluded that conjunctive use of wool waste, farm yard manure and inorganic fertilizer proved better nutrient management option for improving soil properties.