Left atrial ıntramural hematoma after radiofrequency catheter ablation of left lateral accessory pathway

We report a case of left atrial hematoma after ablation of left lateral concealed accessory pathway. A 46-year-old male patient experienced chest pain after radiofrequency ablation. Transthoracic echocardiography and computed tomography revealed the intramural mass consistent with hematoma in the left atrium. He was hemodynamically stable, and conservative approach was decided. Atrioventricular groove is a vulnerable part of left atrium, and ablation of left free wall accessory pathway may require targeting both atrial and ventricular surfaces of the mitral annulus. Avoidance of forceful catheter manipulation during the electrophysiological procedure is important for prevention of this complication. Optimal periprocedural anticoagulation might reduce the risk of procedure-related thromboembolic complications, but electrophysiologists should always pay attention to an intramural hematoma that may occur after radiofrequency catheter ablation.

Left atrial ıntramural hematoma after radiofrequency catheter ablation of left lateral accessory pathway

We report a case of left atrial hematoma after ablation of left lateral concealed accessory pathway. A 46-year-old male patient experienced chest pain after radiofrequency ablation. Transthoracic echocardiography and computed tomography revealed the intramural mass consistent with hematoma in the left atrium. He was hemodynamically stable, and conservative approach was decided. Atrioventricular groove is a vulnerable part of left atrium, and ablation of left free wall accessory pathway may require targeting both atrial and ventricular surfaces of the mitral annulus. Avoidance of forceful catheter manipulation during the electrophysiological procedure is important for prevention of this complication. Optimal periprocedural anticoagulation might reduce the risk of procedure-related thromboembolic complications, but electrophysiologists should always pay attention to an intramural hematoma that may occur after radiofrequency catheter ablation.

Relationship between Pulmonary Artery Stiffness and Functional Capacity in Patients with Heart Failure with Reduced Ejection Fraction

BACKGROUND AND OBJECTIVES: Functional capacity varies significantly among patients with heart failure with reduced ejection fraction (HFrEF), and it remains unclear why functional capacity is severely compromised in some patients with HFrEF while it is preserved in others. In this study, we aimed to evaluate the role of pulmonary artery stiffness (PAS) in the functional status of patients with HFrEF. METHODS: A total of 46 heart failure (HF) patients without overt pulmonary hypertension or right HF and 52 controls were enrolled in the study. PAS was assessed on parasternal short-axis view using pulsed-wave Doppler recording of pulmonary flow one centimeter distal to the pulmonic valve annulus at a speed of 100 mm/sec. PAS was calculated according to the following formula: the ratio of maximum flow velocity shift of pulmonary flow to pulmonary acceleration time. RESULTS: PAS was significantly increased in the HFrEF group compared to the control group (10.53±2.40 vs. 7.41±1.32, p < 0.001). In sub-group analysis of patients with HFrEF, PAS was significantly associated with the functional class of the patients. HFrEF patients with poor New York Heart Association (NYHA) functional capacity had higher PAS compared those with good functional capacity. In multivariate regression analysis, NYHA class was independently correlated with PAS. CONCLUSION: PAS is associated with functional status and should be taken into consideration as an underlying pathophysiological mechanism of dyspnea in patients with HFrEF.

Increased serum uric acid levels are correlated with decreased left atrial appendage peak flow velocity in patients with atrial fibrillation

We aimed to examine the relationship between serum uric acid levels and left atrial appendage [LAA] peak flow velocity, an indicator of the mechanical functions of the LAA, and atrial fibrillation [AF]. Transesophageal echocardiography was performed before cardioversion in 153 patients with AF. The patients were categorized into 2 groups based on their LAA blood flow velocity. Group 1 included 87 patients with a low LAA flow velocity [<35 cm/s], and group 2 comprised 66 patients with a normal LAA flow velocity [>/=35 cm/s]. The chi[2]and Student's t tests were used to compare categorical and quantitative data between the groups. Linear regression analyses were performed to demonstrate the independent association between serum uric acid levels and LAA peak flow velocity. The LAA blood flow velocity was 24.62 +/- 5.90 cm/s in group 1 and 49.28 +/- 13.72 cm/s in group 2, respectively [p < 0.001]. The serum uric acid levels were 6.88 +/- 1.85 mg/dl in group 1 and 5.97 +/- 1.51 mg/dl in group 2, and the difference was statistically significant [p = 0.001]. There was a negative correlation between serum uric acid levels and LAA blood flow velocity [r = -0.216, p = 0.007]. Multivariate regression analysis showed that serum uric acid levels, age and gender differences were significant predictors of the LAA peak flow velocity. High serum uric acid levels were associated with a low contractile function of the LAA and could provide additional prognostic information on future thromboembolic events in patients with AF

QT dispersion increases with low glomerular filtration rate in patients with coronary artery disease

We aimed to evaluate the relationship between estimated glomerular filtration rate [eGFR] and QT dispersion [QTd] in patients with coronary artery disease [CAD]. Sixty patients [mean age 62.72 +/- 12.48 years] included 46 male, [mean age 60.89 +/- 12.70 years] and 14 female [mean age 68.71 +/- 9.86 years] were enrolled in this study. Patients were divided into 2 groups according to their eGFR using the 6 variable MDRD equation. Group 1 consisted of patients with estimated eGFR < 60 ml/min/1.73m[2] and Group 2 consisted of patients with eGFR >/= 60 ml/min/1.73m[2]. Baseline patient characteristics were homogeneous in both groups except for age, gender and smoking. Also, the extent of CAD was similar in both groups [p > 0.05] QTd values were found higher in group 1 than those of group 2 [57.23 +/- 40.65 ms vs. 31.23 +/- 14.47 ms, p = 0.002]. After adjustment for age, gender and smoking using one-way ANCOVA test, statistically significant difference in QTd still existed between the groups [p=0.038]. QTd tends to be higher in patients with poor renal function independent of severity of angiographical CAD. QTd may be a potentially useful non-invasive test in the management of patients with poor renal function, especially those with CAD

Migration of fully deployed stent after intracoronary glyceryl trinitrate administration: an unusual percutaneous coronary intervention complication

Stent embolization is a rare complication of coronary stenting. If left untreated, it may lead to devastating consequences. Although there is much known about stent embolization, data about migration of stent after deployment is limited. We report an unusual case of a deployed stent migration into the distal part of right coronary artery after intracoronary glyceryl trinitrate administration during percutaneous coronary intervention