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China Journal of Chinese Materia Medica ; (24): 50-53, 2002.
Article Dans Chinois | WPRIM | ID: wpr-263641

Résumé

<p><b>OBJECTIVE</b>To investigate the effects and the related mechanisms of the components of Dang-Gui-Bu-Xue decoction (DGBXD) on improving blood deficiency.</p><p><b>METHOD</b>The effects of promoting hematopoietic function were observed with the blood difficient model mice, by giving components of DGBXD. RBC, WBC, reticulocytes and bone marrow nucleated cells (BMNC) were determined. The components of DGBXD on proliferation of BMNC and on clony forming unit (CFU) were also determined.</p><p><b>RESULT</b>The components of DGBXD remarkably increased the quantity of RBC, WBC, and BMNC. Some of the components promoted the proliferation of BMNC and increased the quantity of CFU-Mix. Among them, polysaccharide of angelica was most potent.</p><p><b>CONCLUSION</b>The studies show that the extracts and some components of DGBXD can promote the hemopoietic function system of the model mice, and they exert the effects in a comprehensive way.</p>


Sujets)
Animaux , Femelle , Mâle , Souris , Angelica sinensis , Chimie , Astragalus membranaceus , Chimie , Hémogramme , Cellules de la moelle osseuse , Test clonogénique , Association médicamenteuse , Médicaments issus de plantes chinoises , Pharmacologie , Cellules souches hématopoïétiques , Souris de lignée BALB C , Souris de lignée ICR , Phytothérapie , Extraits de plantes , Pharmacologie , Plantes médicinales , Chimie , Polyosides , Pharmacologie
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