The value of plaque-to-aorta CT value ratio in differentiating coronary lipid and fibrous plaques / 实用放射学杂志

Objective To explore the value of plaque-to-aorta CT value ratio(standardized CT value)in differentiating coronary lipid and fibrous plaques,and to preliminarily analyze the stability of the cutoff.Methods Patients who underwent coronary computed tomography angiography(CCTA)and intravascular ultrasound(IVUS)within 1 week were included.The plaque CT value was obtained by measuring the all,four and two short-axis planes,respectively.The CT value of the ascending aorta was measured and standardized(plaque-to-aorta CT value ratio).The receiver operating characteristic(ROC)curves of the standardized and the traditional CT values were drawn.Results A total of 60 patients with 74 plaques were included,35 lipid and 39 fibrous plaques were diagnosed by IVUS.The aorta CT value was significantly correlated with the plaque(r=0.420,P<0.01);the cutoffs for the CT value of all,four and two plaque slices were 55 HU,48 HU and 52 HU,respectively,and all there of the cutoffs of standardized CT value were 0.149;the sensitivity,specificity,positive predictive value(PPV)and negative predictive value(NPV)of four-slice traditional and standardized CT values to differentiate lipid and fibrous plaques were 69%,87%,83%,76%and 91%,82%,82%,91%,respectively.Conclusion Compared with traditional CT value,the standardized CT value can greatly improve the sensitivity and NPV in differentiating coronary lipid and fibrous plaques,while maintaining modest to high specificity and PPV.Furthermore,the cutoff is stable.

Relationship Between Carotid Atherosclerosis and Traditional Chinese Medical Syndrome Patterns in Aged Patients with Isolated Systolic Hypertension / 广州中医药大学学报

Objective To investigate the relationship between the incidence and degree of carotid atherosclerosis(CAS) and traditional Chinese medical(TCM) syndrome patterns in aged patients with isolated systolic hypertension(ISH).Methods A prospective cohort trial was applied.Thirty healthy volunteers were in the normal control group.One hundred and twenty aged ISH patients were classified into four TCM syndrome patters.The relationship between TCM syndrome patters and CAS was studied.Results The maximum carotid intima-media thickness(IMTmax) was larger in aged ISH patients than the normal control group(P