Relationship of nonsyndromic cleft lip and/or palate and poliovirus receptor-related 1 exon 3 polymorphisms in Han people of Jiangzhe area / 中华整形外科杂志

<p><b>OBJECTIVE</b>To study the relationship of nonsyndromic cleft lip and/or palate (NSCL/P) and poliovirus receptor-related 1 exon3 (PVRL1exon3) polymorphisms in Han People of Jiangzhe area.</p><p><b>METHODS</b>PVRL1exon3 was examined by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technique in the 50 patients with NSCL/P and 85 healthy parents.</p><p><b>RESULTS</b>No W185X mutation was found in the PVRL1exon 3.</p><p><b>CONCLUSION</b>It indicates that there is no relationship between NSCL/P and PVRL1exon3 in Han People in Jiangzhe area.</p>