Discussion on tumor proliferation and metastasis from perspective of neurogenesis / 中国药理学通报

In the tumor microenvironment, tumor cells and nerv e eells infiltrate each other, ultimately promoting the occurrence and development of tumor.Numerous evidence shows that neuro-genesis plays a key role in the regulation of tumor microenviron¬ment.By reviewing the interaction between neurogenesis and tumor and tumor microenvironment.this paper summarizes the factors including nerve growth factor that affects neurogenesis mediated tumor proliferation and metastasis, and the significance of tumor detection and treatment by regulating nerve signal.'Hie purpose of this study is to assist clinical treatment of tumor pro¬liferation and metastasis from the perspective of neurogenesis.

Role of β-adrenergic receptors in development of breast cancer / 中国药理学通报

; β-adrenergic receptors (β-ARs) are widely found in organs of the human body and play an important role in regulating heart function, blood vessel dilation, energy metabolism, etc. Studies have shown that β-ARs are abnormally high in breast cancer cells, which can promote the occurrence and development of breast cancer by affecting the growth and metabolism of breast cancer, invasive metastasis, and angiogenesis. Clinical studies have shown that blocking β-ARs signaling improves the prognosis of breast cancer patients, so β-ARs may be a potential treatment target for breast cancer. This paper summarizes the role of β-ARs in the development of breast cancer, with a view to providing some reference for follow-up research and clinical treatment.