Comparison of wide-angle digital retinal imaging system and binocular indirect ophthalmoscope in retinopathy of prematurity screening / 国际眼科杂志(Guoji Yanke Zazhi)

·AIM:To compare the application effect on patients with retinopathy of prematurity (ROP) screened by wide-angle digital retinal imaging system (RetCam) and binocular indirect ophthalmoscope (BIO). ·METHODS:Totally 1624 cases(3248 eyes) of premature infants were detected by RetCam and BIO in our hospital from May 2014 to May 2017. The screening results of ROP and occurrence of adverse events were compared between two checking methods. ·RESULTS: In the 1 624 cases (3248 eyes) of premature infants,196 cases (392 eyes) of premature infants were detected by RetCam and 189 cases (378 eyes) of premature infants were detected by BIO, there was no statistical significance on staging results and partition pathological results between RetCam and BIO (P>0.05). Taking inspection result of BIO as standard, the sensibility, specificity, false positive rate and positive predictive value was 100. 00%, 99. 51%, 3. 57% and 96.43%, respectively. The adverse event rate of RetCam and BIO was 0.18% and 0.22%, respectively, there was no statistical significance (P>0.05). ·CONCLUSION:RetCam and BIO have similar application efficacy for screening ROP, and RetCam could take the place of BIO as the screening method of ROP.

Value of Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio for Prognostic Evaluation of Diffuse Large B-cell Lymphoma / 中国实验血液学杂志

<p><b>OBJECTIVE</b>To investigate the predictive value of neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) for the patients with diffuse large B-cell lymphoma (DLBCL).</p><p><b>METHODS</b>The clinical data of 57 DLBCL patients admitted in the First Affiliated hospital of Anhui Medical University were analyzed retrospectively. According to ROC curve, the cut-off value for NLR and PLR was deterimined, and the patients were divided into high and low NLR/PLR groups before first chamotherapy. Then the relation of NLR and PLR with overall survival (OS) and progression-free survival (PFS) was analyzed by univariate and multivariate COX regression.</p><p><b>RESULTS</b>The optimal cut-off value for NLR and PLR was 2.915 and 270.27, respectively. NLR at the diagnosis was found to be an independent predictor for OS and PFS by univariate and multivariate analysis, while the PLR was an independent predictor for PFS, but did not affect the OS.</p><p><b>CONCLUSION</b>NLR and PLR may provide additional prognostic information for DLBCL patients.</p>