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OBJECTIVE: To isolate and identify the secondary metabolites of Cordyceps cardinalis for providing reference for the further exploration of the active substance of C. cardinalis and the natural product library of Cordyceps. METHODS: The compounds from C. cardinalis fermentation broth were isolated by silica gel column chromatography, C18 reverse phase silica gel chromatography, Sephadex LH-20 gel column chromatography, TLC and so on. The structures of isolated compound were identified by 1H-NMR, 13C-NMR and MS spectra. RESULTS: Six compounds were isolated from the ethyl acetate extract of C. cardinalis fermentation broth as 5-methyl-1, 3-benzenediol (compound 1), 4-hydroxy-17R-methylincisterol (compound 2), 5α, 8 α-epidioxy-(22E,24R)-ergosta-6,22-dien-3β-ol (compound 3),3β,5α,6β-trihydroxy-(22E,24R)-ergosta-7,22-dien (compound 4), uridine (compound 5), oosporein (compound 6). CONCLUSIONS: Six compounds are isolated from C. cardinalis strain, among which compound 1 and compound 2 are isolated from the genus Cordyceps for the first time.
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Objective To solve the problems in medical equipment utilization,supervision,management,clinical safety and etc.Methods A centralized management and sharing system of medical equipment was developed with functional requirements analysis,C/S architecture and programming.Results The system eliminated the needs for manual accounting and allocation,enhanced medical equipment usage rate and improved equipment borrowing procedure.Conclusion The system contributes to dynamic management and efficacy evaluation of medical equipment,so as the working efficiency can be increased while the costs can be decreased for manpower and materials.
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Objective To design a set of quality control management platform of ECG monitor in order to evaluate the quality of ECG monitor quickly and objectively and monitor and record the whole course of quality control.Methods The quality control platform was designed with the existing ECG monitor quality control methods, the existing detection devices, database technique and digital recognition technique based on neural network.Results The platform could be used for the intelligent data acquisition, data recognition, data analysis and statistics of ECG monitor quality control.Conclusion The platform may enhance the quality control of ECG monitor greatly.
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To develop intelligent informatized system for the quality control of ECG monitor. Based on the platform of PowerBuilder and SQL Server and using scientific management process as the standard, the informa-tized system was developed to cover all aspects of ECG monitor quality control. This informatized system, which closely accorded with related laws and regulations, had graded authority, clear responsibilities, multi functions and easy operation. Computer information technology plays an important role in scientific management system of ECG monitor quality control.
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A stable dark variant separated from photobacterium phosphoreum (A2) was fixed in agar-gel membrane and immobilized onto an exposed end of a fiber-optic linked with bioluminometer. The variant could emit a luminescent signal in the presence of genotoxic agents, such as Mitomycin C (MC). The performance of this whole-cell optical fiber sensor system was examined as a function of several parameters, including gel probe thickness, bacterial cell density, and diameter of the fiber-optic core and working temperature. An optimal response to a model genotoxicant, Mitomycin C, was achieved with agar-bacterial gel membrane: the thickness of gel membrane was about 5 mm; the cell density of bacteria in gel membrane was about 2.0 x 10(7)/ml; the diameter of fiber-optic core was 5.0 mm; the working temperature was 25 degrees C. Under these optimized conditions, the response time was less than 10 h to Mitomycin C, with a lower detection threshold of 0.1 mg/L.
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Techniques de biocapteur , Technologie des fibres optiques , Variation génétique , Mesures de luminescence , Protéines luminescentes , Génétique , Mitomycine , Pharmacologie , Toxicité , Fibres optiques , Photobacterium , Génétique , Transcription génétiqueRésumé
Management on medical equipment is discussed and the utility and benefits are analyzed.Several aspects of management of medical equipment in our hospital are mainly introduced such as purchase,check & acceptance,use,maintenance,metrology and scrapping.
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Present situations of the third class medical station in army hospital are discussed in 3 aspects including the recognition of leaders,actualities of metrology work and situation of metrology personnel.Suggestions on the third class medical station are given as follows: cultivation of personnel to promote the construction of medical metrology station;information sharing to enhance metrology level;broad propaganda on metrology regulations to strengthen supervision;continuous subject construction of medical metrology.
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A stable dark variant separated from photobacterium phosphoreum (A2) was fixed in agar-gel membrane and immobilized onto an exposed end of a fiber-optic linked with bioluminometer. The variant could emit a luminescent signal in the presence of genotoxic agents, such as Mitomycin C (MC). The performance of this whole-cell optical fiber sensor system was examined as a function of several parameters, including gel probe thickness, bacterial cell density, and diameter of the fiber-optic core and working temperature. An optimal response to a model genotoxicant, Mitomycin C, was achieved with agar-bacterial gel membrane: the thickness of gel membrane was about 5 mm; the cell density of bacteria in gel membrane was about 2.0 x 10(7)/ml; the diameter of fiber-optic core was 5.0 mm; the working temperature was 25 degrees C. Under these optimized conditions, the response time was less than 10 h to Mitomycin C, with a lower detection threshold of 0.1 mg/L.
Sujets)
Techniques de biocapteur , Mesures de luminescence , Technologie des fibres optiques , Protéines luminescentes/génétique , Mitomycine/pharmacologie , Mitomycine/toxicité , Photobacterium/génétique , Transcription génétique/effets des médicaments et des substances chimiques , Variation génétiqueRésumé
This paper puts forward existing problems and conflicts in the work of third class medical metrology stations in army,raises suggestions from 5 aspects including enhancing metrology awareness,fulfilling rules,setting strict standards,etc.
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The function of Medical Engineering profession in military hospitals becomes more and more important,so does the development of the professional person troops.There is an urgent need of a professional person troop with high-tech professional knowledge,rigorous science style and good managerial ability.Therefore,it is necessary to develop the professional person troops in Medical Engineering in military hospital.
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This article describes the functions and technical information based on the introduction of classification and theory of the operating table.Considering about the situation of manufacturers and applications,it also analyzes the current application status.According to the experience,it provides a means of maintenance and management.Finally,it introduces some kinds of multi-functions and professional electric operating table,and also figures out the developing trend of the separated electric operating system.
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Objective To establish quality control system for medical equipment to ensure its application safety and quality. Methods All aspects of medical equipment management were analyzed. Results All aspects of medical equipment management had to be paid attention to. Conclusion Keeping Improved quality of medical equipment contributes to the decrease of the doctor-patient dispute.
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Quality control of medical equipment is very important to the diagnostic accuracy and the cure effect. The work of the quality control is the main technical basis of the hospital construction in promoting medical development, and it's also an important content of the modem medical management. The status, causes and countermeasures of medical equipment quality control in military hospital at the present time are analyzed and discussed.
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There existed conflictsin dialyzer reusing among medicine, economics and law in China. The author analyzed the causes and the problems of dialyzer reusing. In China, reusing dialyzer was determined by economical reason. The conclusions were draw that the dialyzer reusing would lessen the pressure of both patients and society, but it would increase the medical risks. Reusing dialyzer consisted with the principle of medical ethics.
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According to the recognition of medical engineering department after the army reform,this paper puts forward some suggestions on the transform and development of medical engineering function.
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Objective To improve the management and utilization of hospital sterilizing devices. Method Strict and operable managerial system was established. Result Hospital sterilizing devices behaved well. Conclusion Just like the purchase, utilization and maintenance of large-scale equipments, the ones of hospital sterilizing devices also should be integrated to optimize their performances.
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Through summarizing medical consumable emergency safeguard mechanism in "5.12 earthquake relief",and combining with the related laws and regulations of the emergency safeguard,the characteristic of the medical consumable emergency safeguard mechanism are analyzed,and then the correlated proposal about which the medical consumable e-mergency mechanism in construction of military hospital emergencies are putted forward.
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By introducing the basic concept and principle, the advantages and characteristics of ASV technology are highlighted. Based on clinical application, suggestions on how to correctly set ASV parameters are given.
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The military hospital's department of medical engineering is limited by authorized size and system.The existing problems in the construction of department of medical equipment are analyzed and some suggestions are given.The construction of department of medical equipment should be made up of three parts: equipment repairing department,medical metrology department and archives department.The construction is also discussed in such aspects as the rules,methods,goals,human resource management,engineer's training program,and reparing mode.
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With the increasingly wide application of advanced science and technology, medical equipment, which reflects the overall strength of the hospital and medical activities, becomes more and more important. Medical equipment raises the level of medical care and increases the hospital income; while meantime, it is also bound to be accompanied by a range of purchase and management problems. The problems of medical equipment purchase and management in hospital are analyzed, and improvement opinions about equipment purchase, approval, use, maintenance and rejection are proposed in order to improve the actuality of equipment purchase and management.