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1.
Chinese Acupuncture & Moxibustion ; (12): 918-922, 2019.
Article Dans Chinois | WPRIM | ID: wpr-776241

Résumé

OBJECTIVE@#To verify the effect of warm acupuncture combined with western medicine in patients with acute exacerbation chronic obstructive pulmonary disease (AECOPD) with phlegm-turbid obstructing of the lung.@*METHODS@#Ninety patients with AECOPD were randomly divided into a western medicine group, a warm acupuncture group and a sham acupuncture group, 30 cases in each group. Routine treatment according to the Global initiative for chronic obstructive lung disease (GOLD) guidelines was used in the western medicine group. On the basis of the routine treatment, the warm acupuncture was applied at Fenglong (ST 40), Feishu (BL 13), Zusanli (ST 36) and other acupoints in the warm acupuncture group. In the sham acupuncture group, non-acupoints were taken on the basis of conventional treatment, and superficial acupuncture was performed for 1-3 mm, once a day for 2 weeks. Forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), FEV1/FVC, cough and sputum assessment questionnaire (CASA), COPD assessment test (CAT), and the change of TCM syndrome score were observed before and after treatment in all groups.@*RESULTS@#After treatment, the FEV1, FVC and FEV1/FVC in each group were higher than those before treatment (0.05). The CASA score, CAT score and TCM syndrome score in each group were lower than those before treatment (0.05).@*CONCLUSION@#Warm acupuncture has a significant effect on the improvement of symptoms in patients with AECOPD with phlegm-turbid obstructing of the lung.


Sujets)
Humains , Points d'acupuncture , Thérapie par acupuncture , Volume expiratoire maximal par seconde , Poumon , Broncho-pneumopathie chronique obstructive , Thérapeutique
2.
Acta Pharmaceutica Sinica ; (12): 199-202, 2015.
Article Dans Anglais | WPRIM | ID: wpr-251795

Résumé

Abstract: A new selaginellin derivative named as selaginellin S (1) was isolated from the whole plants of Selaginella pulvinata (Hook. et Grev.) Maxim. (Selaginellaceae), together with a known one (selaginellin M, 2). Compounds 1 and 2 were separated and purified by silica gel and Sephadex LH-20 column chromatography. Their structures were determined on the basis of extensive spectroscopic analysis including IR, MS, 1D and 2D NMR experiments, as well as ECD calculations. Compound 1 is a key intermidiant in the biosynthesis pathway of selaginellins. Compound 2 is first reported in this plant.


Sujets)
Dérivés du biphényle , Chimie , Cyclohexanones , Chimie , Structure moléculaire , Selaginellaceae , Chimie
3.
China Journal of Orthopaedics and Traumatology ; (12): 258-261, 2012.
Article Dans Chinois | WPRIM | ID: wpr-248849

Résumé

Platelet-rich plasma (PRP) is a kind of plasma with high concentration of platelet,which includes a lot of growth factors. It was widely used in oral and maxillofacial surgery and orthopedics, for the repairing of bone, cartilage and soft tissues. The growth factors, especially PDGF and TGF-beta, plays an important role in different stages and aspects.


Sujets)
Animaux , Humains , Maladies osseuses , Thérapeutique , Régénération osseuse , Os et tissu osseux , Malformations , Plasma riche en plaquettes , Chimie
4.
Chinese Journal of Medical Education Research ; (12): 1296-1298, 2011.
Article Dans Chinois | WPRIM | ID: wpr-671651

Résumé

Thorough excavation and artful utilization of various kinds concrete and invisible learning resources contribute to the cultivation of excellent postgraduates.In postgraduate education of anesthesiology Xuzhou Medical College utilizes time,network,technique platform,research outcome,self-potentiality and clinical patients resources,which produces an active effect and has important instructional significance.

5.
Chinese Journal of Integrated Traditional and Western Medicine ; (12): 418-421, 2009.
Article Dans Chinois | WPRIM | ID: wpr-273682

Résumé

<p><b>OBJECTIVE</b>To investigate the inhibitory effect of arsenic trioxide, aspirin and their combination on the growth of human gastric adenocarcinoma SGC-7901 graft in nude mice.</p><p><b>METHODS</b>Thirty-one model nude mice with transplanted tumor of human gastric adenocarcinoma SGC-7901 were established successfully by fixing tumor tissue under the left axillary subcutaneously. They were randomly divided into 4 groups and treated respectively with normal saline (control group, n = 7), aspirin (Asp group, n = 8), arsenic trioxide (AT group, n = 8), and AT +Asp (combined treated group, n = 8), medicated by intraperitoneal injection for 14 successive days. All mice were sacrificed 48 h after the final medication, the transplanted tumor mass volume and weight were measured to calculate the tumor inhibition rate, and changes of tumors and tissues of heart, liver, and kidney, etc were observed. Moreover, expressions of proliferation associated protein Ki67 and apoptosis inhibitory protein Bcl-2 were detected by immunohistochemical SP method, and expression of apoptosis associated protein Bax was detected by Western blotting.</p><p><b>RESULTS</b>After terminating the medication, in the combined treated group the tumor volume and weight were significantly lower than those in the control group (P < 0.05) and the tumor weight was lower than that in the AT and Asp groups (both P < 0.05). The volume inhibition rate was 59.12% in the AT group, 47.60% in the Asp group, and 76.70% in the combined treated group, and the weight inhibition rate in them 35.60%, 45.44% and 63.90%, respectively. Immunochemical staining showed that as compared with the control group, expressions of Ki67 and Bcl-2 were down-regulated in all the three treated groups to some extent (all P < 0.05), and significant difference was also shown in comparison of the two indices between the combined treated group with the other two treated groups (P < 0.05). The expression of Bax was higher in the combined treated group than in other groups (all P < 0.05).</p><p><b>CONCLUSION</b>Combined use of AT and Asp has certain cooperative effect in inhibiting the growth of gastric carcinoma cells without obvious toxic-side effects.</p>


Sujets)
Animaux , Humains , Souris , Adénocarcinome , Traitement médicamenteux , Composés de l'arsenic , Pharmacologie , Acide acétylsalicylique , Pharmacologie , Antigène KI-67 , Métabolisme , Souris nude , Transplantation tumorale , Oxydes , Pharmacologie , Protéines proto-oncogènes c-bcl-2 , Métabolisme , Tumeurs de l'estomac , Traitement médicamenteux , Protéine Bax , Métabolisme
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