Résumé
Membranous fat necrosis is a variant of fat necrosis characterized by the presence of membranocystic foci which is lined by eosinophilic, homogeneous and crenulated membrane that has pseudopapillary projections. Membranous fat necrosis may be idiopathic or has been associated with many local and systemic diseases. The pathogenesis of membranous fat necrosis is uncertain but trauma may be suspected in our case. We describe a case of lipoma with membranous fat necrosis.
Sujets)
Granulocytes éosinophiles , Stéatonécrose , Lipome , MembranesRésumé
Verruciform xanthoma is a rare benign lesion characterized by verrucous epidermal hyperplasia with aggregates of foam cells in dermal papillae. The pathogenesis is still unknown. Although most verruciform xanthoma tend to occur as isolated lesions, several have been associated with other conditions including squamous cell carcinoma and epidermal atypia. We describe a case of verruciform xanthoma associated with epidermal atypia.
Sujets)
Carcinome épidermoïde , Cellules spumeuses , Hyperplasie , XanthomatoseRésumé
BACKGROUND: Exposure to airborne allergens exacerbates symptoms of atopic dermatitis in sensitive patients. OBJECTIVE: We attempted to evaluate the therapeutic effect of Dermatophagoides farinae antigen-autoantibody immune complex therapy in atopic dermatitis. METHODS: Four patients with atopic dermatitis were treated with antigen-autoantibody immune complex therapy using D. farinae antigen for 1 year. The therapeutic effect was evaluated by clinical severity (erythema, excoriations, scale, pruritus, lichenification) and D. farinae specific antibodies, skin test to D. farinae, total IgE, eosinophil count and soluble vascular cell adhesion molecule-1 (VCAM-1). RESULTS: One of four patients had significant improvement in clinical severity and decrease in serum eosinophil count, but three of four patients had no significant improvement in clinical severity, skin test to D. farinae, total IgE, specific antibodies and soluble VCAM-1 after allergenantibody complex therapy except specific IgE to D. farinae. CONCLUSION: The efficacy of allergen-antibody complex therapy may be limited in some atopic dermatitis patients.
Sujets)
Humains , Allergènes , Anticorps , Complexe antigène-anticorps , Eczéma atopique , Dermatophagoides farinae , Granulocytes éosinophiles , Immunoglobuline E , Prurit , Pyroglyphidae , Tests cutanés , Molécule-1 d'adhérence des cellules vasculairesRésumé
Mondor's disease is a superficial thrombophlebitis of anterolateral chest wall. The exact cause is unclear, but it is suggested that Mondor's disease is often associated with recent local trauma, muscular strain, or breast surgery. We report two cases with Mondor's disease who had malignant lymphoma. The coagulation profile was normal in both patients. The nodule involuted with analgesics within several months. The possibility of Mondor's disease associated with hypercoagulable state from malignancy may be suggested.