Application of 3D printing technology in fracture and deformity of foot and ankle / 中国组织工程研究

BACKGROUND: The anatomical structure of the foot and ankle is complex. There are many extensor and flexor tendons passing through the foot and ankle, which is adjacent to many blood vessels and nerves. The foot and ankle play an important role in human walking, jumping and squatting. As the ankle joint itself is the most distal load-bearing joint of the limb, it is difficult to achieve satisfactory therapeutic effect by traditional methods to treat complex periankle fractures (such as severe comminuted trimalleolar fractures and Pilon fractures), or various severe ankle deformities (such as talipes equinovarus, hallux valgus, and flatfoot). Fortunately, in recent years, 3D printing technology has significantly improved the success rate and patient satisfaction of the above diseases. OBJECTIVE: To summarize the current situation of 3D printing technology in the treatment of ankle fracture and deformity. METHODS: The computer was used to search CNKI, PubMed database. Chinese search terms were “3D printing technology, ankle surgery, ankle fracture, ankle deformity, orthopedics”. The English search terms were “3D printing, foot and ankle surgery, ankle fracture, foot and ankle deformity, orthopedic surgery”. The retrieval period was from January 2000 to February 2020. A total of 105 articles were retrieved. According to the inclusion and exclusion criteria, 55 articles were finally included for review. RESULTS AND CONCLUSION: (1) Through the simulation operation of foot and ankle surgery on 3D physical model, the operator’s proficiency in the operation can be improved. Simultaneously, according to the needs of the operation, individual surgical instruments can be made to improve the success rate of the operation. (2) Compared with the traditional foot orthosis, 3D printing technology can make foot orthosis more suitable for human body structure.

Standardized management of acupuncture-moxibustion clinic in Singapore General Hospital / 中国针灸

The standardized management of acupuncture-moxibustion in Singapore General Hospital is introduced. With gradual improvement of outpatient infrastructure, re-training of medical staff, strict disinfection of manipulation, periodical inspection of medical instruments, unified management of writing, saving and processing in medical records and public education of TCM knowledge, a standardized management system in accordance with modernized hospital is gradually established. As a result, efficiency and quality of clinical treatment is continuously increasing. From April of 1998 to December of 2012, a total of 74 654 times of treatment were performed, and treatment amount per day is gradually increased. The unusual condition of acupuncture is avoided. Periodical strict inspection of joint committee authenticated by domestic and overseas medical health organization is repeatedly passed and accepted. Additionally, three clinical researches funded by Singapore Health-care Company are still in progress in acupuncture-moxibustion department.

Research on mechanism of energy metabolism disorders of rat's hepatoxicity induced by saikosaponins / 中国中药杂志

<p><b>OBJECTIVE</b>To study the influence of saikosaponins on function of rats' liver mitochondria, its liver damage mechanism was discussed.</p><p><b>METHOD</b>Administrating alcohol eluent of saikosaponins of different dose for 15 days to rats, and the high, middle and low lose-group are separately 300, 150, 50 mg x kg(-1) caculated by total saikosaponins. The liver index in serum, the respiratory function of liver mitochondria,the content of ATP and the activity of ATP enzyme were detected. The weight of heart, liver, spleen, lung, renal of rats were precisionly weighed, and the ratio of organ to body were calculated. The histopathologic examination of hepatic tissue were examined.</p><p><b>RESULT</b>Alcohol eluent of saikosaponins of different dose can induce apparent decrease of PCR, P/O value, respiratory oxygen consumption and the activity of ATP enzyme; the level of ALT, AST and ALB in serum increased; the liver weight and the ratio of liver to body increaseed, and the hepatic tissue damage is obvious in the histopathologic examination of hepatic tissue. The above-mentioned changes gradually aggravates with dose increasing, and it is obviously discrepancy compared with control group.</p><p><b>CONCLUSION</b>Alcohol eluent of saikosaponins can induce liver damage by restraining the respiratory function of mitochondria and effecting liver's energy metabolism. Other hepatoxicity mechanism still need to be discussed.</p>