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China Journal of Chinese Materia Medica ; (24): 4261-4274, 2023.
Article Dans Chinois | WPRIM | ID: wpr-1008681

Résumé

Headache is a common clinical complication of ischemic stroke. As a precursor of stroke, headache occurs repeatedly in the convalescent period of ischemic stroke, leading to secondary stroke and seriously hindering patients' rehabilitation. Currently, it is believed that the pathogenesis of ischemic stroke-related headache is associated with the abnormal release of vasoactive substances, high platelet aggregation, and stimulation of intracranial pain-sensitive structures. The active ingredients in traditional Chinese medicines(TCM) with the effects of activating blood to resolve stasis and clearing heat to release exterior can protect brain tissue and relieve headache by reducing the release of inflammatory cytokines, alleviating antioxidant stress, inhibiting neuronal apoptosis and so on. This paper introduces the research progress in the potential mechanism and TCM treatment of ischemic stroke-related headache, aiming to provide reference for further research and drug development of this complication.


Sujets)
Humains , Accident vasculaire cérébral ischémique/traitement médicamenteux , Encéphalopathie ischémique/traitement médicamenteux , Médecine traditionnelle chinoise , Accident vasculaire cérébral/traitement médicamenteux , Céphalée/traitement médicamenteux , Médicaments issus de plantes chinoises/usage thérapeutique
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