Effect of electrochemotherapy in treating patients with venous malformations / 中国结合医学杂志

<p><b>OBJECTIVE</b>To evaluate the efficacy and safety of electrochemotherapy in treating venous malformations.</p><p><b>METHODS</b>Electrochemotherapy was applied to 665 patients with venous malformations of limbs and trunk, and 505 cases were followed up for half to 6 years. In this study, 228 male and 277 female patients were involved. Diagnosis was made by clinical manifestations and magnetic resonance imaging. The platinum electrodes were inserted into tumor through a trocar with plastic insulating cannula percutaneously and connected with the electrochemical therapeutic apparatus in anodes and cathodes separately. Then electricity was given. The treating voltage is 6-12 V and volume 100-180 mA, the total electricity used is in general 80-100 coulombs per 1.0 square centimeter of tumors' area. The treating time was usually from several dozen minutes to over 2 h depending on the size of the tumor. The severe cases which needed to be treated once again usually were operated after 6 months.</p><p><b>RESULTS</b>The primary efficacy end point was defined as an improvement of patients' symptoms and a reduction in size of tumor 6 months after treatment. Effects were divided into 4 grades, and the efficacy rate decreased from grade 1 to grade 4. The efficacy turned out that 30.1% (152/505) of patients was classified as grade 1; 46.3% (234/505) as grade 2; 19.0% (96/505) as grade 3 and 4.6% (23/505) as grade 4.</p><p><b>CONCLUSIONS</b>Electrochemotherapy shows special superiorities in treating venous malformations. It might bring a confirmed clinical efficacy with the advantages of less injury, quick recovery, simple operation and less complications.</p>

Introduction of Electrochemical Therapy (EChT) and Application of EChT to The Breast Tumor / 한국유방암학회지

PURPOSE: To introduce the history and principle mechanism of electrochemical treatment (EChT) with animal study and report two cases successfully treated breast cancer and hemangioma by EChT. METHODS: In animal study, the breast cancer tumor in nude mouse treated with EChT (100 Coulomb/cm3) were reviewed for histologic changes. In the case studies, we reported method of EChT and clinical results after EChT. Case 1: 74 yr old female with locally advanced breast cancer received 3 times EChT with 1,000 Coulomb/time, 8 Volt. Case 2: 51 yr old female with breast hemagioma received one time EChT with 80 Coulomb, 8 Volt. RESULTS: In animal study, There were destructive change including vaculated cell fragment and extensive coagulative necrosis. Case 1 showed no local recurrence during 18 monthes after EChT. Case 2 also showed no evidence of recurrence of hemangioma. CONCLUSION: The EChT is easy to use. It is effective, safe, less traumatic and makes patients recover quickly. This is a new and effective method to treat patients with tumours that are inoperable and can not receive chemotherapy or radiotherapy.

Effect of electro-acupuncture in treating patients with lingual hemangioma / 中国结合医学杂志

<p><b>OBJECTIVE</b>To explore the clinical effect of electro-acupuncture (EA) in treating patients with lingual hemangioma (LHG).</p><p><b>METHODS</b>EA therapy was applied on 36 patients by directly inserting the platinum needles into LHG through a trocar with plastic insulating cannula to protect the normal tissues and connecting the needles with the electro-chemical therapeutic apparatus of model ZAY-B. Then electricity was given until the tumor body got contracted and rigid. The result was assessed 6 months after EA was started.</p><p><b>RESULTS</b>All patients were treated effectively, namely, the effective rate was 100%, with the therapeutic effect reaching grade I in 29 patients (80.6%), grade II in 7 (19.4%), and all having the function of tongue recovered to normal.</p><p><b>CONCLUSION</b>EA shows special superiorities in treating LHG, proved to bring about less injury and quick recovery and being simple in operation. Especially when applied on huge LHG, it could not only remove the tumor, but also preserve the function of the tongue, so it is a brand-new approach that is likely to be accepted by patients.</p>

Replacement of artificial tracheal prosthesis by two-stage procedure with memory-alloy mesh / 中华外科杂志

<p><b>OBJECTIVE</b>To design an artificial trachea which can totally heal with the native trachea.</p><p><b>METHODS</b>Using memory-alloy mesh as the skeleton to construct an artificial trachea by two-stage operation. After 2-year animal experiment we successfully performed the operation in a patient with recurrent carcinoid of the trachea, radically resected the tumor and primarily reconstructed the trachea.</p><p><b>RESULTS</b>The inner side of this "sandwich" artificial tracheal prosthesis was coated with skin and outside the memory-alloy mesh was muscle and vessel pedicle with good blood supply. The upper and lower anastomosis completely healed with recipient's trachea with a full recovery of trachea. Six-month follow-up showed that the patients resumed their normal life.</p><p><b>CONCLUSION</b>The artificial trachea completely healed with the native trachea and became a part of the human trachea. The inner side of artificial trachea is coated with intact native skin tissue with ample blood supply, totally alive without rejection. Therefore, the pedicled artificial tracheal prosthesis is an real artificial trachea.</p>

Observation on effect of electro-acupuncture in treating maxillofacial hemangioma / 中国中西医结合杂志

<p><b>OBJECTIVE</b>To investigate the clinical effect of electro-acupuncture (EA) in treating maxillofacial hemangioma (MFH).</p><p><b>METHODS</b>The platinum needles (electrode) were inserted into the MFH under location and guidance with B-ultrasonography or CT, with the number of needles used according to the size of the MFH to make the distance between needles about 1.5 cm, and the peri-lesional health tissue was protected with plastic insulating tube. The electrodes, which were divided as cathode and anode, were linked with the EA apparatus for EA treatment, the often applied voltage was 5.0-7.0 V, current 60-80 mA and quantity about 100 coulombs/cm of MFH's diameter. B-ultrasonography was used for monitoring during EA, and the treatment would be finished when B-ultrasonography showed disappearance of blood flow.</p><p><b>RESULTS</b>Evaluation according to the WHO's standard for therapeutic efficacy evaluation of tumor showed that after treatment, 345 patients (85.2%) were completely remitted (CR), 39(9.6%) partially remitted (PR), 12(3.0%) improved pathologically, and 9 (2.2%) ineffective, the effective rate (CR + PR) was 94.8%.</p><p><b>CONCLUSION</b>EA, as an creative technique for treatment of MFH, has made breakthrough achievement in clinical practice with high efficacy. It also has the superiorities of simple, less injury, quick recovery, with no scar left and easy to be spread, therefore, it provides an effective method for curing MFH.</p>