Your browser doesn't support javascript.
loading
Montrer: 20 | 50 | 100
Résultats 1 - 3 de 3
Filtre
Ajouter des filtres








Gamme d'année
1.
Chinese Traditional and Herbal Drugs ; (24): 3661-3665, 2015.
Article Dans Chinois | WPRIM | ID: wpr-853807

Résumé

Objective: To optimize formulations of emulsion-hydrogel transdermal patch of essential oil from Artemisia Argyi Folium, and to evaluate its transdermal characteristics in vitro. Methods: The formulations were optimized by orthogonal experiment with four factors including hydrogel patch carrier (sodium polyacrylate NP-700), crosslinking agent (dihydroxyaluminium aminoacetate), crosslinking modifier (EDTA), and moisturizing agent (glycerol). Initial adhesive force, hold force, 180° peeling strength, cohesion, and permeability were measured. In addition, the contents of eucalyptol, camphor, and borneol in hydrogel transdermal patch were analyzed by GC. Results: The impacting factors which affected the patch shaping were in the order of glycerol > dihydroxyaluminium aminoacetate > EDTA > sodium polyacrylate NP-700. The optimized formulation was as following: 30% glycerol, 5% NP-700, 0.3% dihydroxyaluminium aminoacetate, and 0.03% EDTA. The permeation rates of eucalyptol, camphor, and borneol were 85.216, 4.442, and 3.941 μg/(cm2∙h), respectively. Conclusion: Emulsion-hydrogel transdermal patch of essential oil from Artemisia Argyi Folium has a better quality and a transdermal property of zero-order release process.

2.
China Journal of Chinese Materia Medica ; (24): 2039-2041, 2006.
Article Dans Chinois | WPRIM | ID: wpr-246026

Résumé

<p><b>OBJECTIVE</b>To prepare an inclusion complex of daidzein and hydropropyl-beta-cyclodextrin to enhance the solubility of daidzein.</p><p><b>METHOD</b>The inclusion complex of daidzein was prepared by the solution stirring method. The binary system of daidzein and HP-beta-CD was confirmed by differential thermal, thermogravimetry analysis, infrared spectroscopy and X-ray diffractometry.</p><p><b>RESULT</b>The drug content in the inclusion complex was 6. 76% and the solubility was 13.68 mg x mL(-1). The identification results showed that the inclusion complex was formed.</p><p><b>CONCLUSION</b>The preparation method of the inclusion complex of daidzein and hydropropyl-beta-cyclodextrin is simple and available, with a increased solubility of daidzein.</p>


Sujets)
2-Hydroxypropyl-beta-cyclodextrin , Analyse thermique différentielle , Préparation de médicament , Méthodes , Isoflavones , Chimie , Solubilité , Spectroscopie infrarouge à transformée de Fourier , Diffraction des rayons X , Cyclodextrines bêta , Chimie
3.
China Journal of Chinese Materia Medica ; (24): 410-413, 2003.
Article Dans Chinois | WPRIM | ID: wpr-282193

Résumé

<p><b>OBJECTIVE</b>To study the formulation and technique of preparation of rapid-dissoluted EGb (Extract of Ginkgo biloba) droppills.</p><p><b>METHOD</b>Taking the dissolution percentage of total flavonoids in EGb and weight variation as index, the formulation and technique of EGb droppills were optimized by the orthogonal experiment.</p><p><b>RESULT</b>T50 was 3.62 min and mean weight variation was 2.80%.</p><p><b>CONCLUSION</b>Rapid-dissoluted EGb droppills can increase the dissoluting rate distinctly and reach the purpose of preparation.</p>


Sujets)
Stabilité de médicament , Médicaments issus de plantes chinoises , Chimie , Flavonoïdes , Ginkgo biloba , Chimie , Plantes médicinales , Chimie , Solubilité , Technologie pharmaceutique , Méthodes
SÉLECTION CITATIONS
Détails de la recherche