Résumé
Objective:To investigate clinical characteristics of cerebrovascular disease complicated with secondary epilepsy in the elderly, and to provide the targeted health care measures.Methods:The 106 elderly patients with epilepsy secondary to cerebrovascular diseases treated in Three Gorges Hospital Affiliated to Chongqing University were enrolled as the epilepsy group, and another 106 patients with single cerebrovascular disease without secondary epilepsy during same period were included as the control group.Clinical features and epileptic seizure activity were observed and analyzed, and the targeted health care measures were developed.Results:The proportions of patients with cerebral hemorrhage, cerebral lobe infarction, cortical dysfunction and abnormal brain waves were higher in the epilepsy group [ 66.99%(71 cases), 68.87%(73 cases), 83.02%(88 cases), 70.75%(75 cases), respectively]than in the control group(43.40% or 46 cases, 46.23% or 49 cases, 61.32% or 65 cases, 53.77% or 57 cases)( χ2=11.921、11.121、12.424、6.505, all P<0.05). NFD scores before treatment had no significant difference between the epilepsy group and the control group(22.7±4.8 vs.23.4±5.1, t=1.029, P=0.152). NFD score after 3 months of treatment was higher in the epilepsy group than in the control group(14.3±2.9 vs.10.1±2.5, t=11.294, P=0.000). Conclusions:Epilepsy is a common complication of various cerebrovascular diseases, among which the cerebral hemorrhage is the most common.Polyloencephalopathy and cortical involvement can increase the risk of epilepsy in patients with cerebrovascular diseases.Therefore, it is very important to provide the necessary treatment and health care, so as to reduce the impact of epileptic seizure on the disease condition and improve prognosis in patients with cerebrovascular disease.
Résumé
In order to discuss the clinical efficacy of simulation hyperbaric oxygen therapy[HBOT] for severe craniocerebral injury and analyze the related factors of it, 108 patients who transferred to our department during December 2010 - December 2014 for ventilator treatment after operation of severe craniocerebral injury were taken as the subjects of the study. These patients were divided into conventional treatment group and simulation hyperbaric oxygen therapy group to contrast the curative effects. At the meantime, GOS score and length of stay in intensive care unit [ICU] of two groups 6 months after treatment, as well as changes in the indexes of the HBO group during treatment were performed statistical analysis. Then factors affecting prognosis of simulation HBOT were performed regression analysis and principal component analysis. The results showed that when compared to the control group, differences in cases with four GOS score and one GOS score in the treatment group were significant [p0.05]. Regression analysis indicated that factors affecting prognosis included cerebral contusion, coronary heart disease, hydrocephalus and tracheotomy. Principal component analysis found the factors were hydrocephalus, coronary heart disease, tracheotomy, cerebral contusion, cerebral infarction and glasgow coma scale [GCS] before treatment. Therefore, stimulation HBOT can significantly improve the prognosis of patients with severe craniocerebral injury. Paying attention to risk factors in clinics and giving timely interventional treatment can reduce morbidity and mortality in patients