1.
Chinese Pharmacological Bulletin
;
(12): 1061-1066, 2023.
Article
Dans Chinois
| WPRIM
| ID: wpr-1013782
Résumé
Aim To investigate the role and specific mechanisms of muscle factor Irisin in regulating the intracellular protective protein Sirtl and mitochondrial uncoupling protein 2 (UCP2) during myocardial hypoxia. Methods H9c2 cells were treated with CoC12 for 24 hours to construct an in vitro hypoxia model of myocardial cells. Six groups were divided in this experiment; control group (control), Irisin group (10 nmol • L