[Method verification of PTH assay according to the OLAS requirements at the laboratory of Biochemistry and Toxicology of HMIMV]

Method verification[angle qu] of analysis is a requirement of the regulatory quality standard [the Moroccan Guide of Good Execution of the Analyzes] and normative standard [the ISO 15189 standard].Mastery of this approach must be a concern for every practicing biologist. In this work, we present an example of a method verification of the determination of iPTH1-84, on ARCHITECT ci 8200® according to the recommendations of the Luxembourg Office of Accreditation and Surveillance documents [OLAS]. All the results obtained meet the pre-established analytical requirements

[Hemoglobinosis O-Arab: about three cases of incidental discovery during HbA1c assay at the biochemistry-toxicology laboratory of HMIMV in Rabat]

O-Arab hemoglobin, a rare variant of Hb related to a mutation in the HbA beta chain, is asymptomatic hemoglobinopathy in the heterozygous state and is well tolerated in the homozygous state. However, double heterozygosity or heterozygous composite can be in a severe clinical form hence the importance of diagnosis, both in genetic counseling and early management of patients. We report three cases of O-Arab heterozygous haemoglobinopathy discovered incidentally in the HbA1c assay by HPLC on ADAMS [Arkray®]