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Article Dans Anglais | IMSEAR | ID: sea-140070

Résumé

Background: Dry mouth is a common clinical problem, and different products have been proposed to improve it. In this investigation, the effects of "milk curd" on the amount of saliva secretion were studied. Materials and Methods: A total of 32 patients (aged 20-30) were selected from healthy volunteers. Milk curd concentrations of 0.5, 1, 2 and 4%, and 2% pilocarpine were prepared as drops. The impact of the drugs on the saliva weight was assessed after 1-5 min. To determine the effects of the pH of the milk curd on the amount of saliva secretion, different concentrations of acetic acid were used. Results: At the end of the first minute, the differences between the data for all groups were statistically significant, and the difference between the 2% and 4% milk curd groups was higher than the others (P < 0.0001). The differences in the amount of the saliva secreted at the end of the second minute between the baseline and 4% milk curd groups and between the 0.5% and 4% MC groups were significant (P = 0.006 and P = 0.025, respectively). In total, there was no significant difference between the effect of various pH treatments and the amount of baseline saliva secretion. Conclusion: Milk curd has a significant local impact, and the saliva increase depends on the dose. It seems that this effect is not only related to its acidic taste. As a result, factors other than pH are involved in the effect.


Sujets)
Acide acétique/pharmacologie , Adulte , Calcium/analyse , Études croisées , Produits laitiers de culture/composition chimique , Femelle , Humains , Concentration en ions d'hydrogène , Magnésium/analyse , Protéines de lait/analyse , Agonistes muscariniques/administration et posologie , Agonistes muscariniques/pharmacologie , Phosphore/analyse , Pilocarpine/administration et posologie , Pilocarpine/pharmacologie , Placebo , Potassium/analyse , Salive/effets des médicaments et des substances chimiques , Salive/métabolisme , Salivation/effets des médicaments et des substances chimiques , Sodium/analyse , Facteurs temps , Eau/analyse , Jeune adulte
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