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China Journal of Chinese Materia Medica ; (24): 580-583, 2005.
Article Dans Chinois | WPRIM | ID: wpr-279109

Résumé

<p><b>OBJECTIVE</b>To develop a method for quality control of effective fraction in Qi-Xue-Bing-Zhi decoction, a traditional Chinese medicine (TCM).</p><p><b>METHOD</b>PF samples, effective fraction from Qi-Xue-Bing-Zhi decoction, were used as example, and a HPLC assay for chemical fingerprint and quantitative analysis was established.</p><p><b>RESULT</b>The contents range of Paeoniflorin (PE), Naringin (NG) and Neohesperidin (NH) in effective fractions were changed from 12.5%-16.0%, 8.4%-12.4%, 12.8%-15.3%, and their average contents were (14.7 +/- 1.1)%, (10.6 +/- 1.2)%, (14.2 +/- 0.8)% (n = 10), respectively. The fingerprints of PF samples showed 25 common peaks, and the fingerprint similarity for PF samples were all above 99.00% by comparing with the standard chromatogram.</p><p><b>CONCLUSION</b>The method reported could be used effectively for the quality control of effective fraction from TCM.</p>


Sujets)
Benzoates , Composés pontés , Chromatographie en phase liquide à haute performance , Méthodes , Association médicamenteuse , Médicaments issus de plantes chinoises , Flavanones , Glucosides , Hespéridine , Ligusticum , Chimie , Monoterpènes , Paeonia , Chimie , Plantes médicinales , Chimie , Contrôle de qualité , Reproductibilité des résultats
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