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Pakistan Journal of Pharmaceutical Sciences. 2017; 30 (3): 697-703
Dans Anglais | IMEMR | ID: emr-186463

Résumé

The present paper investigates antioxidant, antimicrobial and photochemical screening different extracts of Fagonia olivieri. Analysis of the data indicated that the subject plant contained a good amount of flavonoids, tannins, saponins, terpenoids and steroids. Maximum concentrations of phenolic compounds was found in methanol fraction [29.0+/-6.12 mg GAE/g] while minimum [22.10+/-6.31mg GAE/g] in methylated spirit fraction. Similarly, ethanol fraction contained higher concentration of flavonoid content [135.4+/-7.63mg Quercetin/g] followed by methanol fraction [138.4+/-2.96 mg Quercetin/g]. Analysis of the data revealed that maximum antioxidant activity was recorded in mthylated spirit fraction [IC[50]= 10.69+/-1.66] followed by methanol fraction [IC[50]= 9.10+/-0.76] while no activity was noted in hexane fraction. The data indicated good antibacterial and antifungal activity against S. typhi, S. aureus, P. aeruginosa and A. flavus

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