Résumé
OBJECTIVE: To analyze the effects of long term exposure to power frequency electromagnetic fields( PFEMF) on apoptotic rates of peripheral blood T and B lymphocytes in workers of transformer substation. METHODS: A random number table method was used to select 73 workers with long-term exposure to PFEMF as exposure group and 70 non-exposure workers( administrative and logistics staffs) were selected as control group from 10 transformer substations in a province.The peripheral venous blood of workers in these two groups was collected,and the apoptosis of T and B lymphocytes were detected and analyzed by flow cytometry. RESULTS: The apoptosis rates of T and B lymphocyte between the exposure and non-exposure groups showed no statistical difference( median: 1. 555% vs 0. 790%,0. 020% vs 0. 030%,P > 0. 05).The multivariate linear regression analysis showed that both the PFEMF exposure and length of service had no significant effects on the apoptosis rates of T lymphocyte and B lymphocyte after adjusting confounding factors such as gender,age,alcohol drinking,smoking,medication history,medical radiation exposure and stressful events( P > 0. 05). CONCLUSION: Long-term exposure to PFEMF has no effects on apoptosis of peripheral blood T and B lymphocytes in workers of transformer substation.