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Objective@#To understand the current situation and influencing factors of coping capacity in public health emergencies among college students in Shandong Province, and to provide reference for public health emergencies responses.@*Methods@#Using stratified random sampling method, 7 719 students from 6 colleges and universities in Shandong Province were selected and investigated with self designed questionnaire from April to May 2020. Multiple linear regression was used to analyze the influencing factors of coping capacity in public health emergencies.@*Results@#The overall coping capacity of college students in Shandong Province to public health emergencies scored (46.22±8.47), with dimension from high to low being personal prevention before the event (15.65±2.75), post event cooperation and disposal (15.18±3.08), incident personal precaution (15.01±3.23). Multiple linear regression showed that gender, major, only child, parental education level, knowledge of public health emergencies, emergency drill exercises, and health education for public health emergencies were associated with coping capacity among college students in public health emergencies ( B =-1.53, -1.78, -2.08, 0.60, 0.81, 1.11, 1.38, 0.78, 1.65, 1.86, 9.14, 2.00, 2.62, P <0.05).@*Conclusion@#The overall coping capacity in public health emergencies among college students in Shandong is at a good level, but still needs to be improved through strengthening emergency education and family support.
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Objective@#To evaluate response to public health emergencies in colleges and universities and associated factors, and to provide references for emergency response mechanisms in colleges.@*Methods@#Using stratified random sampling, recruited 7 719 students in 6 universities in Shandong Province during April May 2020, and analyzed the data with SPSS 25.0 software.@*Results@#About 65.5% of college students reported response to public health emergencies in their college, 67.7% of the students reported that colleges have emergency plans, 53.9% of the students reported that colleges have carried out simulated emergency training, and 64.7% of the students reported that colleges have carried out health education. Evaluation from students for responding to public health emergencies in colleges and universities scored(24.15±4.59), of which measures and policies related to epidemic control were highest(4.05±0.81), while mental health education or counselling services were lowest (3.95±0.85). Gender, grade, major, type of household registration, emergency response measures, emergency response plan, emergency simulation training, health education were associated with the evaluation of the measures by college students(t/F=5.04，43.83，79.92，-3.40，26.86，34.83，29.35，35.01，P<0.01).@*Conclusion@#While recognizing the overall performance on public health responses in universities, college students believe certain limitations still exist; colleges and universities should continuously improve the emergency prevention and control system of public health emergencies in response to the effectiveness and deficiencies in the prevention and control process.
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Objective To compare the effects of different doses ofdonepezil,the cholinesterase inhibitor,on patients with mild to moderate Alzheimer's disease (AD) and analyze the correlations of different rating scales of AD so as to choose a better evaluation tool for AD treatment efficacy.Methods Sixty-nine AD patients,admitted to our hospital from January 2010 to November 2010,were randomly divided into 5 mg donepezil treatment group (n=33) and 10 mg donepezil treatment group (n=36); the treatments were given daily for a consecutive 12 months.They were performed Mini Mental State Examination (MMSE),Alzheimer's Disease Assessment Scale-cognitive sub scale (ADAS-cog),activities of daily living (ADL) and instrumental activities of daily living (LADL) every 3 months (3,6,9 and 12 months after the first evaluation time). Results Improvements were noted in both groups on MMSE scores,ADAS-cog scores,ADL scores,IADL scores,and latency of P300 and N200:the MMSE scores,ADAS-cog scores and latency of P300 in the 10 mg treatment group were obviously higher/longer than those in the 5 mg treatment group.Relation between MMSE scores and ADAS-cog scores was noted (r=-0.378,P=0.001).No relation was noted on neuro-psychology and electrophysiology of these patients (P＞0.05). Conclusion Donepezil is safe and effective in improving cognition of patients with mild to moderate AD,and has obvious dose-effect:the efficacy of 10 mg donepezil is superior to that of 5 mg donepezil; the parameters of cognitive assessment in neuro-psychology were found having relation with each other,which can be used with combination to improve the evaluation efficacy.
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Objective To identify the effects of atorvastatin on high-sensitivity C-reactive protein (hs-CRP), yon willebrand factor (vWF), P-selectin, low-density lipoprotein-cholesterol (LDL-C)and carotid intima-media thickness (IMT) of patients with essential hypertension. Methods One hundred and fifty-one patients with mild hypertension were randomly divided into 3 groups: 10 mg atorvastatin, amlodipine and benazepril were daily delivered to group A (n=50); 20 mg atorvastatin,amlodipine and benazepril were daily delivered to group B (n=61); and amlodipine and benazepril were daily delivered to control group (n=40). All patients were assessed for the levels of hs-CRP, vWF,P-selectin, LDL-C and IMT at the baseline and every 3 months. The observation period lasted for 1 y and statistical analysis was performed on these collected data. Results As compared with that in the control group, significant reduction was identified on the levels of hs-CRP, vWF, P-selectin, LDL-C and IMT in group A and group B (P＜0.05). Correlation analysis discovered that the changes of levels of hs-CRP, VWF, P-selectin and IMT did not correlate with the reduction of LDL-C. Conclusion The progression of atherosclerosis can be delayed by atorvastatin in patients with hypertension, which is probably independent from its lipid-lowering function.