Résumé
Extracellular vesicles(EVs)are membrane-derived lipid bilayers secreted by bacteria and eukaryotic cells.EVs se-creted by Gram-negative bacteria have been extensively studied for many years,but due to differences in cell wall structure,EVs in Gram-positive bacteria have been disregarded.However,the production of EVs in Gram-positive bacteria was confirmed in recent stud-ies.Components of EVs are diverse,including proteins,lipids,nucleic acids and metabolites,play important role in biofilm forma-tion,antibiotic resistance,horizontal gene transfer(HGT)and pathogenesis.EVs have potential applications and are involved in the fields of vaccine research and development,disease treatment and drug delivery.Here,we review the latest findings on the biogene-sis,components,applications and functions of EVs from Gram-positive bacteria,hoping to provide a reference for the research in the field of EVs in Gram-positive bacteria.