Ezrin and tumor metastasis / 国际肿瘤学杂志

Ezrin is a member of ezrin-radixin-moesin(ERM)family acting as correlationship between plasma membrane and cytoskeleton,which plays an important role in maintaining shape,polarity,and movement as well as signal transduction of cells.The recent studies indicate that Ezrin abnormally overexpresses in majority of tumor cells,which has close relationship with carcinogenesis,invading and metastasis of tumor cells.