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China Journal of Chinese Materia Medica ; (24): 1016-1019, 2014.
Article Dans Chinois | WPRIM | ID: wpr-321375

Résumé

To establish a method for determination contents of schizandrin, tanshinone I, cryptotanshinone, tanshinone II (A) and schizandrin B in rongxin pills. The HPLC method was performed on an Agilent C18. The mobile phase was composed of methnol and water wish gradient elution. The flow rate was 1.0 mL x min(-1). The column temperature was 30 degrees C and the detection wavelength wash 240 nm. The linear of schizandrin, tanshinone I, cryptotanshinone, Tanshinone II (A) and schizandrin B were 3.000-48.00 (r = 1.000), 3.985-63.76 (r = 0.999 9), 6.370-101.9 (r = 1.000), 8.690-139.0 (r = 0.999 9), 1.700-27.20 mg x L(-1) (r = 0.999 9), respectively. The average recoveries were 98.44%, 100.3%, 99.29%, 99.07%, 98.42%, and RSDs were 0.61%, 1.1%, 0.52%, 0.72%, 0.97%. The method is convenient, accurate and has good precision. It can be used for determination of the preparation.


Sujets)
Chromatographie en phase liquide à haute performance , Cyclooctanes , Abiétanes , Médicaments issus de plantes chinoises , Chimie , Lignanes , Modèles linéaires , Composés chimiques organiques , Phénanthrènes , Composés polycycliques , Contrôle de qualité , Reproductibilité des résultats
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