Childhood Hepatosplenic T-cell Lymphoma with Skin Involvement.

Background: Hepatosplenic T-cell lymphoma is a rare malignancy in childhood. Case characteristics: A 12-year-old boy who presented a pyrexia of unknown origin, multiple skin and lesions and marked hepatosplenomegaly. Observation: Bone marrow aspirate cytology showed no blast cells. Splenectomy was done, and spleen showed infiltration with atypical lymphoid cells positive for CD3, CD8 and T-cell-restricted intracellular antigen. Outcome: The skin rash of patient subsided with chemotherapy. Message: Skin involvement may be an unusual clinical manifestation of hepatosplenic T-cell lymphoma.