RÉSUMÉ
This paper explored the relationship between systemic lupus erythematosus （SLE） and yin-yang toxins based on the discussion of yin-yang toxin in Synopsis of the Golden Chamber （《金匮要略》）， and found that the two are similar in symptoms， and there is a potential relationship between adverse prognosis factors； and the idea that early treatment of SLE can improve prognosis is in accordance with the opinion in traditional Chinese medicine claiming that yin-yang toxin should be diagnosed and treated as soon as possible. Therefore， it is proposed to take yin-yang as general and toxin pathogen as key to explain the pathogenesis， use yin-yang toxin theory for guidance， discuss on the treatment of SLE around the pathological elements including “toxin， heat， stasis”， and take into account of the kidney essence. Accordingly， Shengma Biejia Decoction （升麻鳖甲汤） is recommended as the basic formula with modifications in accordance with different syndromes in staged treatment， providing reference for the clinical diagnosis and treatment of SLE.
RÉSUMÉ
Objective Based on the support of the National Natural Science Foundation of China(NSFC)in the field of insomnia in recent 10 years,the research hotspots were analyzed in order to provide references for researchers in related field.Methods The NSFC official website,NSFC searching website,and LetPub database were comprehensively searched for insomnia related researches in recent 10 years,extract the approved year,funding type,province,supporting unit,amount of funding,subject code,key words and other informa-tion for statistical analysis and visualization.Results The funded projects were mainly general projects,the data shows a fluctuating up-ward trend and multi-disciplinary development,and new technologies and new theories emerge in an endless stream.Supporting units were mainly comprehensive and western medicine colleges and universities,and there was an unbalanced regional development.The re-searches mainly focus on the key words such as neurotransmitters,neural circuits,mechanism research,and traditional Chinese medicine diagnosis and treatment.Conclusion The funding of NSFC is of great significance in the field of insomnia and can effectively promote the development of the discipline.Future research still needs to focus on cutting-edge development,maintain the advantages of disciplines while strengthening the intersection of multi-disciplines,promote the application of new technologies and new ideas,pay attention to the transformation of achievements back-feed clinical,and effectively benefit patients.