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Braz. j. infect. dis ; 25(1): 101541, jan., 2021. tab, graf
Article Dans Anglais | LILACS | ID: biblio-1249297

Résumé

ABSTRACT Organizing pneumonia emerges as a late phase complication of COVID-19. Corticosteroids are standard therapy for organizing pneumonia, but the question of whether an approach with high dose corticosteroids would be beneficial for patients with organizing pneumonia secondary to COVID-19 remains to be answered.Herein we report a series of three patients, one male and two females, mean age 58.3 years old, admitted for COVID-19 with severe pulmonary disease requiring ventilatory support. The patients underwent chest computed tomography scans due to maintained hypoxemia, which showed a pattern compatible with organizing pneumonia. The patients were treated with a high dose of corticosteroids (prednisone 1 mg/kg PO), showing marked clinical improvement, and decreasing oxygen flow ratio demand. They were discharged after a mean period of 6.3 days of hospitalization.Our report suggests that patients with COVID-19 with organizing pneumonia might benefit from high dose corticosteroids as an adjuvant therapy.


Sujets)
Pneumopathie infectieuse/traitement médicamenteux , COVID-19 , Hormones corticosurrénaliennes/effets indésirables , SARS-CoV-2 , Poumon , Adulte d'âge moyen
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