Résumé
Objective To observe influences of thermal insulation at different temperatures on changes of vital signs,and inflammatory factors in children with congenital dislocation of the hip joint during surgery and postoperative rehabilitation.Methods Totally 39 cases of children undergoing congenital dislocation hip surgery under general anesthesia were selected and randomly divided into 32℃,38℃ and 43℃ groups.Children patients in three groups were given forced air heating at 32℃,38℃ and 43℃,respectively.The body temperature and other vital signs of each group were recorded immediately after anesthesia induction and intubation (T0),during surgical biopsy (T1),at 1h after operation(T2),2 h after operation(T3) and at the end of operation(T4).The venous blood was taken at T0 and T4 to determine the serum TGF-β activation,TNF-α,IL-1β and IL-10.Results Compared with T0,the temperature of three groups increased at T1-4 (P＜0.05),and 38℃ group had the most reliable temperature maintenance.Compared with 32℃ and 43℃ groups,serum TNF-α and IL-1β significantly decreased and TGF-β and IL-10 significantly increased in 38℃ group at T4(P＜0.05).Children in 43℃ group developed more cases of fever compared with other two groups,and the difference was significant (P＜0.05).Conclusion Temperatures setting at 32℃,38℃ and 43℃ can guarantee stable vital signs during surgery,and address hypothermia before surgery and during anesthesia induction.Applying 38℃ gas heating can maintain normal intra-operative body temperature and effectively inhibit inflammatory response.
Résumé
Objective To observe influences of thermal insulation at different temperatures on changes of vital signs,and inflammatory factors in children with congenital dislocation of the hip joint during surgery and postoperative rehabilitation.Methods Totally 39 cases of children undergoing congenital dislocation hip surgery under general anesthesia were selected and randomly divided into 32℃,38℃ and 43℃ groups.Children patients in three groups were given forced air heating at 32℃,38℃ and 43℃,respectively.The body temperature and other vital signs of each group were recorded immediately after anesthesia induction and intubation (T0),during surgical biopsy (T1),at 1h after operation(T2),2 h after operation(T3) and at the end of operation(T4).The venous blood was taken at T0 and T4 to determine the serum TGF-β activation,TNF-α,IL-1β and IL-10.Results Compared with T0,the temperature of three groups increased at T1-4 (P＜0.05),and 38℃ group had the most reliable temperature maintenance.Compared with 32℃ and 43℃ groups,serum TNF-α and IL-1β significantly decreased and TGF-β and IL-10 significantly increased in 38℃ group at T4(P＜0.05).Children in 43℃ group developed more cases of fever compared with other two groups,and the difference was significant (P＜0.05).Conclusion Temperatures setting at 32℃,38℃ and 43℃ can guarantee stable vital signs during surgery,and address hypothermia before surgery and during anesthesia induction.Applying 38℃ gas heating can maintain normal intra-operative body temperature and effectively inhibit inflammatory response.