Cerebral Blood Flow(CBF) Study on Moyamoya Disease

The author analyzed the r-CBF data of 19 patients who admitted to the Kyung Hee University Medical Center under the diagnosis of definite "Moyamoya" disease from 1983 to 1992. Seven of them were followed-up from 1 to 18 months. The results were as fllow : 1) In moyamoya disease patients, the mean hemispheric r-CBF has a tendency to be lower than that of healthy persons. 2) In moyamoya disease patients, the ipsilateral r-CBF also shows a tendency to be lower than that of contralateral side. 3) The 133Xe-inhalation method is one of useful methods to evaluate CBF in Moyamoya disease, especially for follow-up. 4) The results of follow-up study for Moyamoya disease by 133Xe-inhalation method corelate very well with the change in clinical status of the patients. 5) In Moyamoya disease patients, the follow-up by means of 133Xe-inhalation method is one of useful methods to select a good candidate for surgical treatment such as STA-MAC anastomosis.

Regional Cerebral Blood Flow in Intracranial Tumors

Reginal cerebral blood flow was measured in 40 patients with intracranial tumors using 133 Xe-inhalation method ; 15 metastatic brain tumors, 11 meningiomas, 14 glioblastoma multiformes. While superficially located meningiomas usually revealed high cortical flow in the tumor area, metastatic brain tumors and glioblastoma multiformes showed low cortical flow. High flow in meningiomas may be related to the vascular proliferation on the tumor surface, low flow in metastatic brain tumors and glioblastoma multiformes may be result from surrounding brain edema. Measurement of rCBF can afford differential diagnostic information in meningiomas, but study is needed further in differenting between metastatic brain tumors and glioblastoma multiformes.