Analysis of the efficacy and safety of erythropoietin for anemia in patients with chronic heart failure / 中国基层医药

ObjectiveTo analyze the efficacy and safety of erythropoietin for anemia in patients with chronic heart failure.Methods66 cases with chronic heart failure were randomly divided into the observation group and the control group.The control group was treated with conventional anti-anemia iron treatment,and the observation group was taken erythropoietin therapy treatment on the basis of the control group.Both of the two groups were treated for 8 weeks continuously.ResultsThere were statistically significant differences between the two groups of patients after 8 weeks of treatment,cardiac function had improvement after treatment than before treatment (P ＜ 0.05 ).The observation group was significantly superior than the control group.The blood data in the two groups were compared,the Hb,RBC of the observation group were significantly increased compared with before treatment,the difference was significant (P ＜ 0.05).The RBC level did not change significantly in the control group before and after treatment.The electronic patient data in the two groups were compared,the LVEF,FS in the observation group and control group improved significantly compared with before treatment,but improvement of the observation group was significantly better than control group.The degree of improvement in the two groups were compared,the difference was significant( P ＜0.05).The SV,CO in the two groups were compared,it increasedsignificantly than before treatment,the difference was significant(P ＜ 0.05).The SV,CO before and after treatment in the control group didn't improve significantly.The E/A before and after treatment didn't improve significantly.The incidence of adverse drug reactions in the two groups showed no significant difference.ConclusionThe level of anemia had a direct impact on the degree of heart function classification.Following the usual treatment of heart failure,taking erythropoietin for anemia in patients with chronic heart treatment could significantly improve the treatment of patients with curative effect,with the advantages of safe,widely used for clinical application.

A Case of Severe Anemia by Necator americanus Infection in Korea

This report describes clinical and parasitological findings of an 82-yr-old female patient who lived in a local rural village and suffered from severe chronic anemia for several years. She was transferred to the National Police Hospital in Seoul for management of severe dyspnea and dizziness. At admission, she showed symptoms or signs of severe anemia. Gastroduodenoscopy observed hyperemic mucosa of the duodenum and discovered numerous moving roundworms on the mucosa. Endoscopy isolated seven of them, which were identified as Necator americanus by characteristic morphology of cutting plates in the buccal cavity. The patient was treated with albendazole and supportive measures for anemia, and her physical condition much improved. This case suggests the possibility that hookworm N. americanus is still transmitted in a remote local mountainous area in Korea.

El programa de suplementación con "Prenatal" para la prevención de la anemia en el embarazo

La anemia por deficiencia de hierro es el más frecuente problema nutricional en nuestro país y en especial en la población de gestantes. Para su prevención y control se utiliza la suplementación con preparados farmacéuticos como una forma práctica y efectiva para aliviar el problema. Para este fin se utiliza en la atención primaria el suplemento prenatal especialmente diseñado para el Programa de Atención Maternoinfantil. En el presente trabajo se exponen conocimientos esenciales del problema, los aspectos básicos para lograr una real efectividad en la acción preventiva y la función que debe desempeñar el médico de la familia en el programa de suplementación con prenatal para la prevención de la anemia en el embarazo.

Iron-deficiency anemia is the most frequent nutritional problem in our country, and specially among pregnant women. For its prevention and control it is used the supplementation with pharmaceutical preparations as a practical and effective way to alleviate the situation. To this end, the prenatal supplement specially designed by the Program of Maternal and Child Care is used at the primary health care level. The essential knowledge of the problem, the basic aspects to achieve a real effectiveness in the preventive action, and the role the family physician should played in the supplementation program with prenatal for the prevention of anemia during pregnancy are approached in this paper.