Résumé
Abstract: Acne fulminans is a rare and severe variant of acne. In Brazilian medical journals, cases are infrequently reported, confirming its rarity. We followed five young male patients with this severe variant of cutaneous lesions, accompanied by also severe systemic symptoms: fever, anorexia, weight loss, and arthralgia. All had a good response to corticosteroids (prednisone), but had significant scarring.
Sujets)
Humains , Mâle , Adolescent , Jeune adulte , Acné juvénile/complications , Acné juvénile/anatomopathologie , Arthralgie/étiologie , Fièvre/étiologie , Propionibacterium acnes/immunologie , Indice de gravité de la maladie , Prednisone/usage thérapeutique , Acné juvénile/traitement médicamenteux , Superantigènes/immunologie , Évolution de la maladie , Glucocorticoïdes/usage thérapeutique , NécroseRésumé
Acne fulminans (AF) is a rare severe form of acne associated with systemic symptoms. It primarily affects male adolescents and is clinically characterized by painful ulcerative nodules on the face, chest, and back. The associated systemic symptoms, such as fever, myalgia, and arthralgia, are usually present at the onset. The etiology of AF remains unknown, but there are many theories, such as increased androgens, autoimmune complex disease, and genetic predisposition. Treatment can be challenging because its response to traditional acne therapies is poor. A combination of oral steroids and isotretinoin is the most recommended treatment. Herein, we report a case of a 16-year-old Korean man with acne fulminans presenting with tender, hemorrhagic, crusted, inflammatory nodules on the upper chest, which occurred after isotretinoin use. After treatment with oral isotretinoin and pulsed dye laser for 23 weeks, most of the lesions healed leaving some scars.
Sujets)
Adolescent , Humains , Acné juvénile , Androgènes , Arthralgie , Cicatrice , Fièvre , Prédisposition génétique à une maladie , Isotrétinoïne , Lasers à colorant , Myalgie , Stéroïdes , Thorax , UlcèreRésumé
Acne fulminans is a rare, severe and destructive disease with the acute onset of painful, nodulocystic, ulcerative, acneiform lesions and frequently associated with systemic signs and symptoms including fever, weight loss, myalgia, arthralgia, and leukocytosis. We herein present a 20-year-old male patient with acne fulminans that was successfully treated with combination therapy of oral isotretinoin and systemic corticosteroid.