Résumé
A clinical study was retrospectively made on 33 patients with prostatic adenocarcinoma who were admitted to the Department of Urology, Eulji General Hospital, Seoul and DaeJeon between May 1985 and April 1992. The results were as follows: 1. The age distribution range was from 47 to 86 years (mean age 68.2 years). 2. The major presentations were prostatism (69%), acute urinary retention, gross hematuria and pain. On digital rectal examination, 14 patients (42.4%) had hard nodules on the prostate, and 7 patients had multiple nodules. 3. The clinical stages were stage A in 2 cases, stage B in 3, stage C in 8, and stage D in 20. The grades were: grade I in 7 cases, grade II in 14 and grade III in 12. Distant metastasis was round in 28 patients (84.8%). The sites involved were bone in 20 patients, lymph node in 5 patients, lune, liver and kidney in 1 patient each. Skeletal sites most frequently involved were spine (65%), pelvis (55%) and rib (50%). 4. For the treatment of 28 patients, orchiectomy only (9), DES only (7), DES +orchiectomy (3), endocrine therapy(orchiectomy or DES) + irradiation (8) and radical prostatectomy + irradiation (1) were performed. 5. In the response rate of treated 28 patients, partial or stable response 12 cases (42.9%) and progression 16 cases(57.l%). 7 patients expired, the causes of death were multiple metastasis with cachexia (4), sepsis (2) and congestive heart failure (1).