Efectividad en la suplementación con omega 3 (Pescado) y vitamina D durante el periodo gestacional para la prevención de diversas alergias en el lactante de 0-1 año de edad / Effectiveness in the omega 3 (Fish) and vitamin D supplementation during the gestational period for the prevention of various allergies in the 0-1 year old infant / Eficácia na suplementação de ômega 3 (peixe) e vitamina D durante o período gestacional para a prevenção de várias alergias na criança de 0 a 1 ano

Resumen El objetivo de esta investigación fue describir la efectividad de la suplementación con omega 3 (pescado) y vitamina D durante la etapa gestacional para la prevención de diversas alergias en el lactante de 0 a 1 año. Se presenta los resultados de una compilación y categorización de la mejor evidencia científica disponible. Se aplicó la metodología sugerida para la práctica clínica basada en la evidencia, la cual inició con el establecimiento de una pregunta clínica seguido por la búsqueda de la información en las bases de datos Medline, Science Direct y Cochrane Library, obteniendo 334 artículos de los cuales al aplicar los criterios de selección se conservan 9. Luego se llevó a cabo un análisis crítico utilizando la plataforma FLC 2.0 y clasificando la evidencia por su calidad y grados de recomendación según Canadian TaskForce on Preventive Health Care.Se concluye que a pesar de que los beneficios de la vitamina D y el omega 3 son múltiples, y que el uso en conjunto de ambos en el embarazo, podría significar una mejora no solo sobre la salud materna sino también sobre el feto y lactante; al no contar con estudios con resultados contundentes, no se puede generalizar o recomendar en la práctica clínica.

Abstract The objective of this research was to describe the effectiveness of omega 3 (fish) and vitamin D supplementation during the gestational stage for the prevention of various allergies in infants aged 0 to 1 year. The results of a compilation and categorization of the best available scientific evidence are presented. The methodology suggested for the clinical practice based on the evidence was applied, which began with the establishment of a clinical question followed by the search of the information in the Medline, Science Direct and Cochrane Library databases, obtaining 334 articles of which when the selection criteria are applied, they are kept 9. Then, a critical analysis was carried out using the FLC 2.0 platform and the evidence was classified by its quality and degrees of recommendation according to the Canadian Task Force on Preventive Health Care. It is concluded that although the benefits of vitamin D and omega 3 are multiple, and that the joint use of both in pregnancy, could mean an improvement not only on maternal health but also on the fetus and infant; By not having studies with conclusive results, it can not be generalized or recommended in clinical practice.

Resumo O objetivo desta pesquisa foi descrever a eficácia da suplementação de ômega 3 (peixe) e vitamina D durante o estágio gestacional para a prevenção de várias alergias em lactentes de 0 a 1 ano de idade. Os resultados de uma compilação e categorização das melhores evidências científicas disponíveis são apresentados. Foi aplicada a metodologia sugerida para a prática clínica baseada na evidência, que começou com o estabelecimento de uma questão clínica seguida pela busca da informação nos bancos de dados da Medline, Science Direct e Cochrane Library, obtendo 334 artigos dos quais quando os critérios de seleção são aplicados, eles são mantidos 9. Então, uma análise crítica foi realizada usando a plataforma FLC 2.0 e a evidência foi classificada por sua qualidade e graus de recomendação de acordo com a Canadian Task Force on Preventive Health Care. Conclui-se que, embora os benefícios da vitamina D e omega 3 sejam múltiplos e que o uso conjunto de ambos na gravidez, pode significar uma melhora não só na saúde materna, mas também no feto e no bebê; Ao não ter estudos com resultados conclusivos, não pode ser generalizada ou recomendada na prática clínica.

How Different Parts of the World Provide New Insights Into Food Allergy

The prevalence and patterns of food allergy are highly variable in different parts of the world. Differences in food allergy epidemiology may be attributed to a complex interplay of genetic, epigenetic, and environmental factors, suggesting that mechanisms of food allergy may differ in various global populations. Genetic polymorphisms, migration, climate, and infant feeding practices all modulate food allergy risk, and possibly also the efficacy of interventions aimed at primary prevention of food allergy development. Approaches to diagnosis, treatment, and prevention of food allergy should thus be tailored carefully to each population's unique genetic and environmental make-up. Future research in the context of food allergy prevention should focus on elucidating factors determining differential responses between populations.

Latex allergy: an emerging / Alergia ao látex: um problema emergente / Alergia al latex: an emergentes

Objectives: The current review presents the pathogenic mechanisms, diagnostic and therapeutic and preventive measures to avoid the development of complications related to latex allergy. Method: Literature search electronically from articles already published on the basis of the NCBI / PUBMED / MEDLINE. Results: Manifestations of latex allergy are related to immediate hypersensitivity such as urticaria, angioedema, asthma or even anaphylaxis, or delayed hypersensitivity by a mechanism such as allergic contact dermatitis or primary irritation. Conclusion: Prevention of exposure, replacement and use of latex-free products such as synthetic gloves are essential for those affected. Adjustments in the workplace should be done with gloves without talc, low in allergens or synthetic gloves. These preventive measures significantly reduce the prevalence of allergic reactions.

Objetivos: A revisão atual apresenta os mecanismos imunopatológicos, diagnóstico e medidas terapêuticas e preventivas para evitar o desenvolvimento de complicações relacionadas à alergia ao látex. Método: Pesquisa bibliográfica por meio eletrônico a partir de artigos já publicados, na base do NCBI/PUBMED/MEDLINE. Resultados: As manifestações de alergia ao látex estão relacionadas com hipersensibilidade imediata como a urticária, o angioedema, a asma ou até anafilaxia, ou por mecanismo de hipersensibilidade tardia como a dermatite de contato alérgica ou por irritação primária. Conclusão: Prevenção à exposição, substituição e utilização de produtos livres de látex, como luvas sintéticas são essenciais para os afetados. Adaptações no local de trabalho devem ser feitas com uso de luvas sem talco, com baixo teor de alérgenos ou luvas sintéticas. Estas medidas preventivas reduzem significativamente a prevalência de reações alérgicas.

Objetivos: En esta revisión presentamos los mecanismos patogénicos, diagnóstico y medidas terapéuticas y preventivas para evitar el desarrollo de complicaciones relacionadas con la alergia al látex. Método: La búsqueda bibliográfica electrónica de artículos ya publicados sobre la base de la Revista / PubMed / MEDLINE. Resultados: Las manifestaciones de la alergia al látex se relacionan con la hipersensibilidad inmediata como urticaria, angioedema, asma o incluso anafilaxia o hipersensibilidad retardada por un mecanismo como la dermatitis de contacto alérgica o irritación primaria. Conclusión: Prevención de la exposición, la sustitución y el uso de látex libres de productos tales como guantes sintéticos son esenciales para las personas afectadas. Ajustes en el lugar de trabajo se debe hacer con guantes sin talco, con bajo contenido de alergenos o guantes sintéticos. Estas medidas preventivas reducen significativamente la prevalencia de las reacciones alérgicas.

The role of polyunsaturated fatty acids in allergic diseases prevention / 国际儿科学杂志

Studies suggested a link between the declining consumption of n-3 polyunsaturated fatty acids (n-3 PUFA)and the rise in allergic diseases. Although the effect of supplementing n-3 PUFA on the treatment of atopic diseases in adult has been disappointing, the epidemiological evidence suggested n-3 polyunsaturated fatty acids may play a role in against allergy. In recent years, there has been a growing focus on the role of n-3 PUFA in allergy prevention in early life. This review will examine the current evidences about the effects and mechanisms of n-3 polyunsaturated fatty acids in allergy protection.

Effectiveness of education for control of house dust mites and cockroaches in Seoul, Korea

We evaluated the efficacy of health education in reducing indoor arthropod allergens in Seoul. The mite control measures comprised the use of mite-proof mattress and pillow coverings, regular washing of potentially infested materials, maintenance of a low humidity, removal of carpets, and frequent vacuum cleaning. Cockroach control measures included trapping, application of insecticides, and protecting food. Of 201 homes enrolled in October 1999, 63 volunteers were included in a 2-year follow-up survey between April 2000 and January 2002. Before intervention, the density of mites/g of dust varied greatly; 27.1/g in children's bedding, 20/g in adult bedding, 7.2/g on the floors of children's bedrooms, 6.8/g in sofas, 5.9/g on the floors of adult's bedrooms, 3.9/g on living room floors, 3.7/g in carpets, and 1.9 mites/g on kitchen floors. The predominant mite species and house percentages infested were; Dermatophagoides farinae 93%, D. pteronyssinus 9%, and Tyrophagus putrescentiae 8%. Comparing 1999 and 2001 infestations, before and after 25 mo of education, mite abundance was reduced by 98%, from 23.7 to 0.57 mites/g of dust. In 1999, cockroaches were detected in 62% homes: 36% Blattella germanica and 35% Periplaneta spp., including 9% double infestations of B. germanica and P. americana. Following intervention, cockroach infestation rates decreased to 22% of houses in 2000 and 23% in 2001. We conclude that continuous and repetitive health education resulted in the effective control of domestic arthropods.