Assessment Of Gingival Phenotype At The Aesthetic Zone In A Malay Population Using Probe Test

@#Introduction: The gingival phenotype (GP) of teeth at the aesthetic zone often influences dental rehabilitation plans and treatment outcomes. This study aimed to assess the prevalence of GP in the Malay population in relation to gender and age. Methods: The GP of 100 patients were determined using the Probe test method. Other clinical parameters were assessed include crown width/crown length (CW/CL) ratio, tooth morphology and width of keratinised tissue. Periodontal parameters were assessed by two calibrated examiners. Data were analysed using descriptive statistics, one-way ANOVA and Kruskal-Wallis test. Results: A higher prevalence of thick GP was found at the maxilla for both genders, whereas a thin phenotype was observed at the mandible. At maxilla, both thick and thin GP were found in all age groups, while the mandible showed a higher prevalence of thin GP. Significant differences in GP were found between males and females for mandibular and maxillary anterior teeth and the mandibular lateral incisor (p<0.05), while no significant difference was found for other parameters assessed; age group, CW/CL, tooth morphology and WKT. Conclusion: Thicker GP is more prevalent in male population and at maxillary anterior. Mandibular anterior GP presented commonly with a thin GP regardless of gender or age-group.

Prediction of CW chord after cataract surgery from IOL Master 700 measurement data based on SVR algorithm and BP neural network / 国际眼科杂志(Guoji Yanke Zazhi)

AIM: To observe the changes in the Chang-Warning chord(CW chord)before and after cataract surgery using the IOL Master 700 and predict the CW chord using an artificial intelligence prediction model and preoperative measurement data.METHODS: The analysis was conducted on the preoperative and postoperative IOL Master 700 measurements of 304 cataract patients. This included astigmatism vector value, average keratometry, axial length, anterior chamber depth, lens thickness, corneal central thickness, white-to-white, the position of the Purkinje reflex I image relative to the corneal center and pupil center, and the CW chord. A prediction model based on the SVR algorithm and the BP neural network algorithm was established to predict the postoperative CW chord using the preoperative CW chord and ocular biological parameters.RESULTS: The X component of the CW chord showed a slight shift in the temporal direction in both the left and right eyes after cataract surgery, while the Y component changed little. The SVR model, using the preoperative CW chord and other preoperative biometric parameters as input data, was able to predict the X and Y components of the CW chord more accurately than the BP neural network.CONCLUSION: The CW chord can be directly measured with a coaxial fixation light using various biometers, corneal topographers, or tomographers. The use of the SVR algorithm can accurately predict the postoperative CW chord before cataract surgery.

Correlation between HLA-Cw*0602 and LCE3B_LCE3C-del allele interaction and psoriasis vulgaris in a population of Mongolian nationality in Inner Mongolia / 中国基层医药

Objective:To investigate the effect of HLA-Cw*0602 and LCE3B_LCE3C-del allele interaction on the risk of psoriasis vulgaris in a population of Mongolian nationality in Inner Mongolia. Methods:A total of 365 Mongolian patients with psoriasis vulgaris who received treatment in The Affiliated Hospital of Inner Mongolia Medical University from January 2006 to December 2015 (case group) and 284 healthy subjects who concurrently received physical examination in the same hospital (control group) were included in this study. After sex and age matching, and quality control, the correlations between HLA-Cw*0602 and LCE3B_LCE3C-del allele and psoriasis vulgaris in a population of Mongolian nationality were analyzed using SPSS 20.0 software. The interaction between HLA-Cw*0602 and LCE3B_LCE3C-del alleles (adjusting for potential confounders including age and sex) was analyzed using logistic regression. Results:Logistic regression interaction item Int of dominant inheritance mode HLA-Cw*0602 allele and recessive inheritance mode LCE3C_LCE3B-del allele revealed OR = 2.38, P = 0.033, and interaction index S = 1.21, indicating that there was a synergistic effect between the two alleles. Conclusion:The co-existence of HLA-Cw*0602 and LCE3B_LCE3C-del may increase the risk of psoriasis vulgaris in a population of Mongolian nationality in Inner Mongolia.

A new species of Corydoras Lacépède, 1803 (Siluriformes: Callichthyidae) from the río Madre de Dios basin, Peru

A new species of Corydoras is described from the río Madre de Dios basin, Peru. The new species can be distinguished from its congeners by presenting the following features: a longitudinal black stripe along midline of flank; mesethmoid short, with anterior portion poorly developed; serrations on posterior margin of pectoral spine directed towards the tip of the spine; dorsal fin with the region of the first branched ray, including membrane, with concentration of black pigmentation, the remaining areas with irregular black blotches; absence of a vertically elongated black blotch across the eyes; conspicuously rounded moderately-developed black spots on the snout; and ventral expansion of infraorbital 1 moderately developed.

Uma espécie nova de Corydoras é descrita da bacia do rio Madre de Dios, Peru. A espécie nova pode ser distinguida de suas congêneres por apresentar as seguintes características: uma faixa preta longitudinal ao longo da linha mediana do flanco; mesetmóide curto, com porção anterior pouco desenvolvida; serrilhas na margem posterior do espinho peitoral voltadas em direção à ponta do espinho; região do primeiro raio ramificado da nadadeira dorsal, incluindo membranas, com concentração de pigmentação preta, as demais áreas com manchas pretas irregulares; ausência de uma mancha preta verticalmente alongada através dos olhos; manchas pretas moderadamente desenvolvidas, conspicuamente arredondadas, no focinho; e expansão ventral do infraorbital 1 moderadamente desenvolvida.

A chemical terrorist attack in the post-CWC era / 军事医学

Chemical weapons(CW), as weapons of mass destruction on the battlefield , made their debut in the First World War of the last century .To achieve total prohibition on CW , the international community concluded the Chemical Weapons Convention(CWC)in 1993, and it came into force in 1997.So far, only seven countries have been outside the CWC.The offensive and defensive pattern of the world changed then , and the world began to enter the post-CW era.A chemical terrorist attack perspective is needed in consideration of chemical threats facing the world .This article summarizes the experience on specific chemical attacks , analyzes the possibility , sources, types and developments of a chemical terror-ist attack, and puts forward countermeasures for any possible chemical terrorist attack .

Caracterização e classificação dos resíduos de construção civil da cidade de Fortaleza (CE) / Characterization and classification of construction waste in Fortaleza (CE)

Este estudo visa analisar a composição gravimétrica, avaliar parâmetros químicos e classificar os Resíduos de Construção Civil (RCC) da cidade de Fortaleza de acordo com a Resolução CONAMA nº 307 e com a NBR 10004. Os resultados indicam que o RCC de Fortaleza é composto por 93,40% do Grupo A, 6,40% do Grupo B, 0,02% do Grupo C e 0,20% Grupo D. O primeiro é composto principalmente por areia e solo (24,65%) e argamassa (22,00%), que são materiais com alto potencial de reutilização ou reciclagem. Além disso, de acordo com a análise química, o RCC de Fortaleza mostrou alta variabilidade em todos os parâmetros. Cr, Pb e SO4²-, por exemplo, apresentaram valores acima dos limites especificados pela NBR 10004, indicando que esse material deve ser classificado como Classe II-A (não perigoso e não inerte).

This study aims to analyze the gravimetric composition, evaluate chemical parameters and classify the construction waste (CW) of Fortaleza city according to CONAMA Resolution Nº 307 and to NBR 10004. Results show that Fortaleza's CW is composed by 93,40% of Group A, 6,40% Group B, 0,02% Group C and 0,2% Group D. The first is composed primarily by sand and gravel (24,65%) and mortar (22,00%), that are materials with high potential for reuse or recycling. Moreover, according to chemical analysis, Fortaleza's CW showed a high variability in all parameters. Cr, Pb and SO4²-, for example, showed above to the limits specified by NBR 10004, indicating that this material have to be classified as Class II-A (not dangerous and not inert).

Association between HLA-Cw polymorphism and inflammatory bowel disease / 中华内科杂志

ObjectiveTo investigate the association of HLA-Cw alleles with inflammatory bowel disease(IBD), so as to identify IBD susceptibility gene.MethodsThe HLA-Cw genotype were analyzed in 100 patients with ulcerative colitis (UC), 73 patients with Crohn's disease (CD) and 106 randomly ethnically matched healthy controls by sequence specific primer polymerase chain (PCR-SSP).Results HLA-Cw * 07 gene phenotype frequencies increased in patients with UC (0.430) compared with that in healthy controls (0.226), P = 0.002; while HLA-Cw * 12 gene phenotype frequencies increased in patients with CD (0.356) compared with that in healthy controls (0.123), P = 0.000.ConclusionHLA-Cw * 07 allele and HLA-Cw * 12 allele may be strongly associated with the susceptibility of UC and CD, respectively.

Relationship of HLA-A, -Cw Polymorphisms with HIV/AIDS in Chinese Yi Ethnic Group of Sichuan Province / 中国病毒学

The relationship of HLA-A, -Cw alleles on HIV infection and AIDS disease progression in the Chinese Yi ethnic group of Sichuan province were investigated. The genetic polymorphisms of HLA-A, -Cw alleles of 102 unrelated healthy Chinese Yi ethnic individuals, 68 HIV-1 infected and 21 HIV positive long-time survivors were typed by PCR-SSP assay. Statistic signifiance was determined by the χ2 test with the SPSS software. No significant differences were observed between the HLA-A, -Cw alleles of the 68 HIV-1 infected and 102 non-infected Chinese Yi control individuals. Whereas the prevalence of A*3601,Cw*14(01-03)and Cw*0304 was significantly higher in 21 long time survivors compared with 102 healthy controls with P values of 0.016, 0.016 and 0.000 by χ2 or the Fisher exact test respectively. The result implies that A*3601,Cw*14(01-03) and Cw*0304 may be associated with slow AIDS disease progression in the Chinese Yi ethnic group, further studies on this association may yield insight on the pathogenesis of HIV-1 infection.

Construction of psoriasis susceptibility gene / 中国药理学通报

Aim To prepare for psoriasis transgenic animals, psoriasis susceptible gene was constructed. Methods Extract gDNA from blood preparations of psoriasis patients, screen positive gDNA owns HLA-Cw*0602 gene, then copy the whole sequence and link it to pMD-19T Simple Vector. Results The identification showed the construction of psoriasis susceptible gene was sucessful. Conclusion The successful construction of HLA-Cw*0602 gene will lay the foundation for development of transgenic animal models of psoriasis.

Correlations Between HLA-Cw*0602 and Clinical Picture in Korean Psoriatic Patients / 대한피부과학회지

BACKGROUND: HLA-Cw6 has the strongest individual association with psoriasis in many racial groups, and associations with the positive family history and early age at onset have been noted in many studies. OBJECTIVE: The aim of this study was to investigate whether Cw6 correlate with the clinical parameters of Korean psoriatic patients. METHODS: One hundred and twelve unrelated patients with psoriasis, and 166 healthy controls were examined with regard to Cw*0602, using a PCR-SSP method. We divided the patients into two groups according to Cw*0602 positivity, and compared two groups with reference to several clinical parameters. RESULTS: The results are summarized as follows: 1. Cw*0602 was found in 69.6% of the 112 patients, but only in 9.0% of the 166 healthy controls(p<0.05, RR=23.1). 2. The presence of Cw*0602 correlated with early age at onset(26.1 vs. 32.5 years, p<0.05), and Cw*0602 was present in 75.0% of the patients with early onset(p<0.05, RR=30.2). 3. The presence of Cw*0602 did not correlate with a positive family history of psoriasis among the first-degree relatives, but correlated with an overall positive family history (p<0.05). 4. There were no positive correlations with arthritis, the history of inpatient treatment, the clinical type of psoriasis, and onset or exacerbation after upper respiratory infection. CONCLUSION: The presence of Cw*0602 correlated with a positive family history for psoriasis and early age at onset, but did not correlate with arthritis, the history of inpatient treatment, the clinical type of psoriasis, and onset or exacerbation after upper respiratory infection.

Comparison of HLA-Cw Typing by Serology and PCR-SSP in the Korean Population / 대한임상병리학회지

BACKGROUND: Using the classical serological methods, the HLA-Cw typing resulted in a high frequency of Cw blank because of the lack of suitable antisera coupled with low cell surface expression. Recent data on association between graft-versus-host disease and serologically undetectable HLA-Cw mismatches in bone marrow transplantation (BMT) facilitate the investigations into the biological role of HLA-Cw and more reliable HLA-Cw typing. METHODS: We performed the HLA-Cw DNA typing using PCR-SSP technique with sequence-specific primers of 22 pairs in 150 Koreans (79 organ transplant recipients, 71 healthy potential donors). These results were compared with those of serological HLA-Cw typing, which had been performed by complement-dependent microlymphocytotoxicity technique using Terasaki Tissue typing tray. RESULTs: Comparison between serological and PCR-SSP typing revealed a discrepancy rate of 24.0% (36/150). The majority of total discrepancies (29/36, 80.6%) were due to antigens that were not detected serologically and these antigens consisted of mainly Cw*12 and Cw*15. In five cases, no Cw allele was detected by DNA typing, whereas serological typing showed antigens and different antigen assignments between two methods were found in three cases. Of 66 individuals typed serologically with one blank, 66.6% (44 cases) were confirmed to be homozygous, whereas an additional Cw allele was found in remaining 22 cases using the PCR-SSP technique. In the case of the serologically undetectable HLA-Cw blank antigens, the gene frequencies of Cw*12 and Cw*15 were 6.4% and 2.8%, respectively. CONCLUSIONS: These results indicated that serological typing is insufficient for accurate HLA-Cw typing. DNA typing using PCR-SSP technique appears a reliable and practical method for accurate HLA-Cw typing which can contribute to the evaluation of the biological role of the HLA-Cw in transplantation.

The gene frequencies of HLA-Cw in Guangdong Han population and its significance / 中国免疫学杂志

Objective:To explore the gene frequencies of HLA-Cw and to analyze the recognition characteristic between HLA-Cw and KIR in Guangdong Han population.Methods:An auto semi-quantitative PCR-RSSO method was adopted to detect the HLA-Cw genotypes of a sample of 122 bone marrow donors.Results:The gene frequencies of HLA-CW 03,07,01,08,04,14,15,12,06,05,16 were 0.237 1 , 0.215 9 , 0.175 2 , 0.112 9 , 0.050 5 , 0.041 9 , 0.041 9 , 0.037 6 , 0.033 3 , 0.008 2 , 0.004 1 respectively.HLA-Cw 02,04,05,06 belong to “group 1” recognizing KIR-2DL1/2DS1.HLA-Cw 01,03,07,08 belong to “group 2” recognizing KIR-2DL2/2DL3;2DS2/2DS3.There was a significant difference between the two groups in total HLA-Cw gene frequencies in Guangdong Han population( P