Résumé
Childhood granulomatous periorificial dermatitis (CGPD) is a distinctive granulomatous form of perioral dermatitis. It is characterized by papular eruptions located around the mouth, nose, and eyes, and rarely present eczematous patches or plaques. Histopathologic examination shows upper dermal and perifollicular granulomatous infiltrates. Herein, we report two cases of CGPD that were presented with erythematous plaques. One patient was treated with 0.03% topical tacrolimus and the other patient with oral metronidazole. The patients responded well to their respective therapies, showing resolution of the lesions.
Sujets)
Humains , Dermatite , Dermatite périorale , Métronidazole , Bouche , Nez , TacrolimusRésumé
Childhood granulomatous periorificial dermatitis (CGPD) is a distinctive granulomatous form of perioral dermatitis. It is characterized by papular eruptions located around the mouth, nose, and eyes, and rarely present eczematous patches or plaques. Histopathologic examination shows upper dermal and perifollicular granulomatous infiltrates. Herein, we report two cases of CGPD that were presented with erythematous plaques. One patient was treated with 0.03% topical tacrolimus and the other patient with oral metronidazole. The patients responded well to their respective therapies, showing resolution of the lesions.
Sujets)
Humains , Dermatite , Dermatite périorale , Métronidazole , Bouche , Nez , TacrolimusRésumé
Childhood granulomatous periorificial dermatitis (CGPD) is a self-limiting and well-recognized entity. A six-year-old male child, a known case of juvenile rheumatoid arthritis (JRA) presented with multiple red raised and yellowish lesions over the face, neck, trunk and upper extremities since one month with occasional itching. Cutaneous examination revealed multiple erythematous scaly papules of size up to 5 mm around the mouth, nose and periorbital areas, neck, trunk and upper extremities with few excoriations. Lesional skin biopsy was pathognomic of CGPD. We report a six-year-old Indian male child with extra-facial involvement and healing with small atrophic pigmented scars in a known case of JRA.
Résumé
Childhood granulomatous periorificial dermatitis is a distinctive granulomatous form of perioral dermatitis, characterized by a monomorphous, small papular eruption around the mouth, nose, and eyes. It occurs primarily in prepubertal children. We present a case of a 12-year-old boy with multiple, asymptomatic, erythematous papules on the perioral, perinasal and periorbital areas for 5 months. Histopathological examination revealed upper dermal and perifollicular granulomatous infiltrate. After using oral dapsone 25 mg daily for 7 weeks, the skin lesions were considerably improved. But, 3 months after discontinuence of dapsone, exacerbation of the skin lesions occurred.
Sujets)
Enfant , Humains , Dapsone , Dermatite , Dermatite périorale , Oeil , Bouche , Nez , PeauRésumé
Childhood granulomatous periorificial dermatitis (CGPD) is a benign facial eruption of unknown etiology characterized by a monomorphic papular eruption occurring in the perinasal, perioral, and periocular areas. We report an 11-year-old boy with characteristic features of CGPD. He presented with a 4-month history of non-pruritic, papular eruptions on the face. The histopathologic exam revealed an upper dermal granuloma with surrounding lymphocytes. Treatment was initiated with tetracycline 500 mg/day, but there was no response for 3 weeks. We tried 0.03% topical tacrolimus to treat recalcitrant skin lesions. After 10 weeks of treatment, the lesions resolved without scarring.
Sujets)
Enfant , Humains , Cicatrice , Dermatite , Granulome , Lymphocytes , Peau , Tacrolimus , TétracyclineRésumé
Childhood granulomatous periorificial dermatitis (CGPD), also known as facial Afro-Caribbean childhood eruption (FACE), is a distinctive granulomatous form of perioral dermatitis. It is a condition of unknown etiology, characterized by monomorphous, small, papular eruptions around the mouth, nose and eyes that histopathologically show a granulomatous pattern. It affects prepubescent children of both sexes and typically persists for several months but resolved without scarring. We report a 9 year-old girl with multiple, discrete, monomorphic, papular eruptions of 2-months duration on the perioral and periocular areas. Histopathological examination demonstrated upper dermal and perifollicular granulomatous infiltrate.
Sujets)
Enfant , Humains , Cicatrice , Dermatite , Dermatite périorale , Oeil , Bouche , NezRésumé
Childhood granulomatous periorificial dermatitis is a granulomatous disease that's characterized by monomorphous, small papular eruptions around the mouth, nose and eyes. The condition is benign and self-limiting and it is not associated with systemic involvement. We recently encountered a 7-year-old Korean boy with multiple, discrete, monomorphic, papular eruptions of 4-week duration on the perioral, periocular and perinasal areas. Histopathological examination revealed an upper dermal and perifollicular granulomatous infiltrate. He was treated with oral erythromycin and the condition resolved without leaving any scar.
Sujets)
Enfant , Humains , Cicatrice , Dermatite , Érythromycine , Oeil , Bouche , NezRésumé
Childhood granulomatous periorificial dermatitis (CGPD) is a benign, facial eruption primarily of prepubertal children. It is a distinctive granulomatous process of unknown etiology and is characterized by monomorphic, yellow-brown papules limited to the perioral, perinasal, and periocular regions. The condition is self-limiting and is not associated with systemic manifestations. It can usually be distinguished from sarcoidosis on clinical and histological grounds. We report a case of childhood granulomatous periorificial dermatitis in a 9 year-old boy who had suffered from pruritic erythematous papules around mouth and eyelids. (Korean J Dermatol 2004;42(10): 1333~1336)