Chlamydia Trachomatis Infection in Ectopic Pregnancy: A Case Control Study

Ectopic pregnancy is a significant cause of maternal morbidityand mortality. It is the leading cause of pregnancy relateddeath in the first trimester and account for 9% of all pregnancyrelated death. Ectopic pregnancy refers to the implantation offertilized ovum on any tissue other than the endometrium of theuterus. The main objective of this study is to evaluate theassociation of Chlamydia trachomatis infection in women withectopic pregnancy. To do so, acase control study wasconducted on 90 patients admitted with ectopic pregnancy inthe inpatient department and early normal pregnancy whocome in antenatal clinical and OPD of dept. of Obstetrics &Gynaecology of BSMMU, DMCH, SSMC MH, Dhaka. Thestudy duration was almost three years from the start of January2006 to July 2009. In the present investigation, the resultsshowed that 13.33% & 16.67% had positive IgM and IgG inectopic pregnancy and only 3.33% had positive IgG in normalpregnancy. Total 9 cases (IgM-4& IgG-5) were positive inectopic pregnancy &only 2 cases were positive in normalpregnancy. The difference was statistically significant.Regarding other variables significant difference was present inoccupation of husband, past medical & surgical history.Contraceptive history showed that there was significantdifference between women of ectopic pregnancy and normalpregnancy in oral contraceptive pill use. Regarding pastobstetric history-repeat ectopic pregnancy was 13.3%.Thusly,chlamydia can cause pelvic inflammatory disease which canresult in scarring of the fallopian, with consequent ectopicpregnancies which can be fatal, have reached to morbidity &mortality. Ectopic pregnancy is an important cause of maternaldeath and still holds a diagnostic challenge.

Daños y consecuencias de Chlamydia trachomatis en mujeres infértiles / Damage and Consequences of Chlamydia Trachomatis in Infertile Women

Introducción: La infertilidad ha aumentado a nivel mundial como consecuencia del incremento de las infecciones de transmisión sexual y la enfermedad inflamatoria pélvica producidas fundamentalmente por Chlamydia trachomatis. Objetivo: Describir la relación existente entre la Chlamydia trachomatis y sus daños y consecuencias en mujeres infértiles. Métodos: Se estudiaron 552 mujeres, con diagnóstico de infertilidad y se selecciona una muestra de 175, con diagnóstico de infección por Chlamydia trachomatis. Resultados: Las mujeres en el estudio tenían una escolaridad media superior. La mayoría de las mujeres a pesar de padecer una infección por Chlamydia trachomatis no presentaron daño a órganos reproductores; y en las que sí, predominó la obstrucción tubaria bilateral. En los casos en que se diagnosticó daño al cuello uterino predominó la cervicitis. Conclusiones: La mayoría de las mujeres infértiles con infección por Chlamydia trachomatis eran adultas jóvenes con nivel escolar medio superior, con una infertilidad secundaria y sin daños estructurales en las trompas de Falopio y el cérvix uterino. Existe relación entre la Chlamydia trachomatis y la afección a las trompas de Falopio y el cérvix uterino(AU)

Introduction: Infertility has increased worldwide because of the increase in sexually transmitted infections and pelvic inflammatory disease caused mainly by Chlamydia trachomatis. Objective: To describe the relationship between Chlamydia trachomatis and its damages and consequences in infertile women. Methods: We studied 552 women with a diagnosis of infertility and we selected a sample of 175, with diagnosis of Chlamydia trachomatis infection. Results: The women in the study had high school level. Most of them did not have reproductive organ damage despite suffering from Chlamydia trachomatis infection. However, those who did not have this damage had bilateral tubal obstruction. Cervicitis predominated in those cases in which damage to the cervix was diagnosed. Conclusions: Most of the infertile women with Chlamydia trachomatis infection were young adults with a high school level, suffering secondary infertility and with no structural damage to the fallopian tubes and uterine cervix. There is a relationship between Chlamydia trachomatis and the affection to the fallopian tubes and uterine cervix(AU)

Infección por Chlamydia trachomatis / Chlamydia trachomatis infection

Determinar la prevalencia de la infección por Chlamydia trachomatis en una población de parejas infértiles. Validar la eficacia del diagnóstico de anticuerpos anti Chlamydia para tratar, prevenir y controlar la infección por C. trachomatis. Justificar la necesidad de implementar el monitoreo de rutina para administrar el tratamiento oportuno de la infección por C. trachomatis. Se determinó la prevalencia de la infección por Chlamydia trachomatis en 4 619 pacientes, 2607 mujeres y 2012 hombres en edades reproductivas, entre 1999 y 2008 por problemas de infertilidad. Se detectaron anticuerpos anti-Chlamydia trachomatis (IgG, IgA e IgM) por SeroELISA (Savyon Diagnostics Ltd.) de 1999 a 2005; desde 2006 hasta 2008 se utilizó el kit InmunoComb II (Orgenics). Centro de fertilidad UNIFERTES, Caracas, Venezuela. Se encontró una prevalencia en mujeres de 25,40 ± 6,26 por ciento; y en los hombres de 31,12 ± 2,88 por ciento. La prevalencia de la infección por C. trachomatis en parejas infértiles es alta y no ha disminuido en los últimos 10 años. Se recomienda implementar en Venezuela un monitoreo de rutina para el diagnóstico de C. trachomatis, incluyendo su determinación en el control ginecológico anual y en las evaluaciones urológicas a hombres jóvenes, a fin de prevenir que la infección pase a ser crónica

To determine the prevalence of Chlamydia trachomatis infection in infertile couples. To evaluate the efficiency of the Chlamydia trachomatis screening programs. To establish the need of implementing the routine early diagnosis and opportune treatment of the infection. Prevalence of Chlamydia trachomatis infection was determined in 4619 patients, 2607 women and 2012 men in reproductive agesbetween 1999 and 2008. Anti-chlamydia and C.trachomatis antobodies (IgG, IgA and IgM) were detected by SeroELISA (Savyon Diagnostics Ltd.) from 1999 to 2005; and by the ImmunoComb II kit (Orgenics) from 2006 to 2008. Fertility clinic UNIFERTES in Caracas, Venezuela. A prevalence of 25,40 ± 6,26 percent was found in women and a prevalence of 31,12 ± 2,88 percent was found in men. Prevalence of the C. trachomatis infection in infertile couples is high and has not decreased over the last 10 years. Implementation of routine screening programs for C. trachomatis detection is recommended, including its assessment in annual gynecological controls, as well as in urologic evaluations in young men, in order to prevent the infection from being chronic

A Case of Peritoneal Inclusion Cyst caused by Chlamydia Trachomatis Infection / 대한산부인과학회지

Peritoneal inclusion cysts are fluid collections among adhesions occurring after an inflammatory process in the peritoneal cavity or after an operation. The typical ultrasound morphology of a peritoneal inclusion cyst is that of a cystic mass following the contours of the pelvis, and with a deformed ovary suspended among adhesions centrally or peripherally in the cyst, and the cyst may contain both septa and papillary projection. So sometimes it is difficult to distinguish an ovarian mass from peritoneal inclusion cyst. We experienced one case of huge peritoneal inclusion cyst caused by chlamydia trachomatis infection and then we report it together with a brief review of literatures.