Clinical effects of Zhenzhumingmu eye drops combing with antibiotic in treatment of chronic conjunctivitis / 中国生化药物杂志

Objective To observe clinical effects of Zhenzhumingmu eye drops combing with antibiotic in treatment of chronic conjunctivitis.Methods 96 patients with chronic conjunctivitis from ophthalmology department from January 2015 to October 2016 were grouped two groups by draw method,each with 48 cases.The control group was treated with ofloxacin eye drops,and observation group was treated with Zhenzhumingmu eye drops combing with ofloxacin eye drops.Related indicators are analyzed in two groups.Results ①Effective rate of observation group was 87.50%,higher than control group with 66.67%(P<0.05).②Dry eye, eye itching, eye fatigue and foreign body sensation score of observation group were (1.01±0.24),(0.93±0.22),(0.85±0.18),(0.81±0.25)points,lower than control group(1.46±0.30),(1.39±0.25),(1.16±0.21),(1.22±0.29)(all P<0.05).③Eye discomfort proportion of observation group was 12.50%, higher than control group 8.33%,but the difference was not statistically significant.Conclusion Zhenzhumingmu eye drops has exact curative effect in treatment of chronic conjunctivitis,can improve the symptoms and has high security.

Tracoma: ainda uma importante causa de cegueira / Trachoma: still being an important blinding disease

O Tracoma é uma doença milenarmente conhecida e que persiste como causa de cegueira entre nós. As autoras chamam a atenção para os fatores relacionados com a transmissão, apresentam dados históricos e de distribuição da doença no Brasil e no mundo, comentam sobre o agente, os sinais e os sintomas desta conjuntivite crônica. Ainda reforçam a necessidade de capacitar os profissionais para o diagnóstico, o que possibilitará a detecção e tratamento. O reflexo destas atitudes será a contribuição para a eliminação desta importante causa de cegueira do nosso meio.

Trachoma is a disease known thousand years ago and still as a potential blindness disease all over the world. The authors call attention to the factors related with the transmission, present historical data and distribution of the disease in Brazil and in the world, comment on the agent, the signs and symptoms of this chronic conjunctivitis. Still, reinforce the need to enable professionals for the diagnosis, detection and treatment.The reflection of these attitudes will be the contribution to the elimination of this important disease as a blindness cause among us.

Histological Progress Observation of Conjunctival MALToma

PURPOSE: We report six cases of histologically diagnosed conjunctival MALT (mucosa-associated lymphoid tissue)oma. Presenting symptoms were eyelid swelling, foreign body sensation, lid mass, injection and itching sensation. PATIENTS AND METHODS: Six patients with conjunctival MALToma were followed. Clinical progress and biopsy result were reviewed periodically. RESULTS: The conjunctival MALToma seemed to be localized and slowly progressive. Although the conjunctival MALToma is known to be well responsive to radiotherapy, two of three patients who received radiotherapy revealed to have remnant lymphoma cells histologically in conjunctival biopsy. In addition, chemotherapy did not have curative effect in any of the patients. CONCLUSIONS: Therefore, we are doubtful for the necessity of active treatment in MALTomas of the conjunctiva.

Ocular Cicatricial Pemphigoid

Ocular cicatricial pemphigoid isa chronic, progressive disease characterized by cicatricial shrinkage of the conjunctiva, entropion, trichiasis, xerosis, and finally reduced vision from corneal opacification. It is a relatively rare, autoimmune disease. In the early stages, it can be easily overlooked as simple chronic conjunctivitis, so it can be untreated. We report a case of ocular cicatricial pemphigoid that resulted in significant morbidity. We were able to control the progression of cicatrization with aggressive immunosuppressive therapy.

Acanthamoeba Keratitis: Case Report

We experienced chronic relapsing central corneal ulcer and chronic conjunctivitis with mucoid discharge. Both patients were transfered to our hospital because of no improvement with long term treatment of broad spectrum antibiotics topically and systemically Specimens from corneal scraping and conjunctival mucoid discharge were examined with calcofluor white staining method. We could find a narrow rim of light green colored cystic wall and orange red colored cytoplasm in dark field fluorescent microscopy in both cases, and those were diagnosed as Acnthamoebic cyst by pathologist. We couldn't find any report about ocular Aanthamoeba infections in Korea. To our knowledge, this is the first case report about ocular Acanthamoebic infections in Korea.