Dyslipidemia in Diabetic Patients with Acute Myocardial Infarction

The present study was undertaken to check the lipid profile in patients of acute myocardial infarction withchronic diabetes and to evaluate the variations in various lipid levels in different age, gender and in patientswith different habits of diet, smoking and alcohol consumption. A total of 92 subjects aged between 40-70years were included. 5 ml of fasting blood sample was collected from antecubital vein under aseptic precautionsin a plain vacutainer and incubated at room temperature; serum was separated by centrifuge machine at 2000rpm for 5 minutes. The samples were analyzed for estimation of four biochemical parameters: total cholesterol,serum triglyceride, serum HDL and blood sugar using Abott Architect Autoanalyser. Mean levels of HDL werebelow the normal range in smokers and non-vegetarians whereas mean TG levels were elevated amongalcoholics, smokers and non-vegetarians. High TG levels and low HDL levels are the predominant lipidabnormalities in chronic diabetic patients with AMI. There is also a significant association between smokingand these parameters.

Study of Morphometry and Elastic Fibre Distribution in Left and Right Coronary Arteries.

Background: Coronary artery disease also called asischemic heart disease which develops when majorblood vessels that supply blood to heart becomedamaged or diseased. It is also one of the leading causesof death. Morphometry and elastic fibre distribution incoronary arteries may help in using appropriate sizecatheters for diagnostic procedures. Aim andObjectives: To study the morphometry and elastic fibredistribution in left and right coronary artery. Materialand Methods: Segment of left and right coronaryarteries each having length of 0.5 cm were collectedfrom 30 adult human heart specimens fixed in 10%formalin. Outer and inner diameters were measured.Tissues were processed and stained by verhoeff's VanGeison stain. Stained slides were scanned by “IScapture software” under 10 × magnifications. Results:Outer diameter of left coronary artery is 4.225 ±0.6963mm and right coronary artery is 3.827 ±0.6869mm. Inner diameter of left coronary artery is3.338 ± 0.5853 and that of right coronary is 2.869 ±0.6104mm.Conclusion: Diameter, wall thickness,thickness of tunica intima, tunica media is more in leftcoronary artery than the right. Also left coronary arteryshows more number of elastic fibers than right coronaryartery.